Dopamine Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB00499 | Triflupromazine HCl | 1098-60-8 | Triflupromazine HCl, an antipsychotic, can function as a blocker of dopamine D2 receptor and dopamine D3 receptor in brain. It is used to treat dyskinesia and alcohol withdrawal syndrome. |
| FB00498 | Trifluoperazine | 117-89-5 | Trifluoperazine is a typical antipsychotic of the phenothiazine chemical class. |
| FB05721 | Trifluoperazine 2HCl | 440-17-5 | Trifluoperazine 2HCl is a dopamine D2 receptor inhibitor with anti-dopaminergic and anti-adrenergic actions, which belongs to the phenothiazine compounds. |
| FB00176 | Tiapride HCl | 51012-33-0 | Tiapride HCl is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. |
| FB01672 | Tetrahydropalmatine | 2934-97-6 | Tetrahydropalmatine is an isoquinoline alkaloid mainly found in the genus Corydalis with analgesic effects. It antagonizes dopamine D1, and D2 receptors as well as actions at dopamine D3, alpha adrenergic and serotonin receptors, with Ki values of 124 nM and 388 nM for D1 and D2 dopamine receptors, respectively. |
| FB00065 | Tetrahydroberberine | 522-97-4 | Tetrahydroberberine is an isoquinoline alkaloid isolated and purified from the barks of Phellodendron chinense Schneid. It has micromolar affinity for dopamine D(2) (pK (i) = 6.08) and 5-HT(1A) (pK (i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors(5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK (i) < 5.00). |
| FB09648 | Talipexole | 101626-70-4 | Talipexole is a dopamine agonist that has been proposed as an antiparkinsonian agent. |
| FB02907 | Sumanirole Maleate | 179386-44-8 | Sumanirole maleate is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. |
| FB07327 | Sulpiride | 15676-16-1 | Sulpiride is a typical antipsychotic drug that binds to dopamine D2 receptor. Sulpiride is an effective treatment for schizophrenia and depressive disorder. |
| FB09620 | SKF-82958 | 80751-65-1 | SKF-82958 is a D1/D5 receptor full agonist. |
| FB09464 | SKF-38393 HCl | 62717-42-4 | SKF-38393 HCl is an agonist of dopamine D1 receptor (the IC50 value is 110 nM). It has anorectic and stimulant effects. |
| FB09089 | Rotundine | 483-14-7 | Rotundine is antagonist for domapmine D1 receptor(Ki = 124 nM) and has a lower binding activity of domapmine D2 receptor and domapmine D3 receptor. It can also inhibit 5-HT1A (Ki = 340 nM). |
| FB09088 | Rotigotine | 99755-59-6 | Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. |
| FB01461 | Rotigotine HCl | 125572-93-2 | Rotigotine HCl is an agonist of dopamine D2 receptor and dopamine D3 receptor with Ki of 13 and 0.71 nM respectively. |
| FB01656 | Ropinirole HCl | 91374-20-8 | Ropinirole HCl selectively inhibit dopamine D2 receptor with Ki of 29 nM. It is used for the treatment of spontaneous parkinson's disease. |
| FB08956 | Quinagolide HCl | 94424-50-7 | Quinagolide HCl is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor. |
| FB08581 | Promazine HCl | 53-60-1 | Promazine HCl is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia. |
| FB00133 | Prochlorperazine Dimaleate | 84-02-6 | Prochlorperazine dimaleate is an antagonist of dopamine (D2) receptor with Ki value of 4.7 nM. |
| FB08182 | Pramipexole | 104632-26-0 | Pramipexole is an agonist of dopamine receptors D2, D3, and D4 (Ki = 3.9, 2.2, 0.5, and 5.1 nM respectively) and it is indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS). |
| FB04229 | Pramipexole 2HCl H2O | 191217-81-9 | Pramipexole 2HClis a non-ergoline dopamine (DA) agonist, used to treat Parkinson's disease. |
| FB08527 | Pramipexole 2HCl | 104632-25-9 | Pramipexole 2HCl is an dopamine agonist and can inhibit multiple dopamine receptors including dopamine D2S receptor, dopamine D2L receptor, dopamine D3 receptor, and dopamine D4 receptor with respectively Ki values of 3.9, 2.2, 0.5 and 5.1 nM. |
| FB08176 | Phenothiazine | 92-84-2 | Phenothiazine, a dopamine2 (D2) receptor antagonist, could reduce the expression of dopamine in the brain. |
| FB08142 | Perphenazine | 58-39-9 | Perphenazine is an inhibitor of 5-HT2A receptor(5-HT2A), alpha-1A adrenergic receptor (α1A), dopamine D2 receptor/dopamine D3 receptor, D2L receptor, and Histamine H1 receptor ( Kis = 5.6, 10, 0.765/0.13, 3.4, and 8 nM respectively). It is commonly used as a typical antipsychotic drug. |
| FB08136 | Pergolide | 66104-22-1 | Pergolide is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease. |
| FB01472 | PD 128907 HCl | 112960-16-4 | PD 128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor. |
| FB09762 | Octopamine HCl | 770-05-8 | Octopamine HCl, an adrenoceptor (AR) agonist, is an endogenous biogenic amine that is structurally similar to norepinephrine that could stimulate lipolysis via activation of β3-AR receptors in mammalian adipocytes.It is one of many micro-biamines prevalent in the nervous system of invertebrates. |
| FB07681 | Nomifensine Maleate | 32795-47-4 | Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder. |
| FB07680 | Nomifensine | 24526-64-5 | Nomifensine is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. |
| FB07468 | Neuromedin N | 92169-45-4 | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. |
| FB01335 | MPTP HCl | 23007-85-4 | MPTP HCl is a neurotoxin that causes symptoms similar to parkinson's disease by destroying dopamine-producing nerve cells in the substantia nigra. It is widely used in the study of various animal models of Parkinson's disease. |
| FB06522 | Mosapramine | 89419-40-9 | Mosapramine is an atypical antipsychotic used in Japan. It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors. |
| FB06316 | Molindone HCl | 15622-65-8 | Molindone HCl, the salt form of molindone which is a dopamine receptor antagonist, can be used in the treatment of schizophrenia and act as a therapeutic antipsychotic. |
| FB05918 | Metoclopramide | 364-62-5 | Metoclopramide is an antagonist of dopamine D2 and is commonly used as an antiemetic. |
| FB10643 | Metoclopramide HCl | 7232-21-5 | Metoclopramide HCl is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting. |
| FB04172 | Metergoline | 17692-51-2 | Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors. |
| FB03419 | Levosulpiride | 23672-07-3 | Levosulpiride, an atypical antipsychotic, can selectively inhibit D2 receptor and it is the (S)-enantiomer of sulpiride. |
| FB10659 | Levodopa | 59-92-7 | Levodopa is a prodrug of dopamine (DA) that has been to treat parkinson's symptoms. It can enter the central nervous system through the blood-brain barrier and is generally converted to DA by dopa decarboxylase to exert pharmacological effects. |
| FB07675 | L-Stepholidine | 16562-13-3 | L-Stepholidine is a naturally occurring chemical compound isolated and purfied from the roots of Stephania japonica. L-Stepholidine is a dual D2 receptor antagonist and D1 receptor agonist. |
| FB03084 | Itopride | 122898-67-3 | Itopride is a prokinetic benzamide derivative unlike metoclopramide or domperidone, and is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions. |
| FB01866 | Fluphenazine 2HCl | 146-56-5 | Fluphenazine 2HCl is a inhibitor of D1DR and D2DR. It has been used to deliver fluphenazine to biological systems and also used as an antipsychotic. |
| FB08822 | Flupenthixol 2HCl | 51529-01-2 | Flupenthixol 2HCl, a typical antipsychotic drug, is non-selective antagonist of dopamine D1-5 receptors as well as 5-HT2A. It is also known as flupenthixol. |
| FB01796 | Fipexide | 34161-24-5 | Fipexide is a psychoactive drug of the piperazine chemical class, used as a nootropic drug, mainly for the treatment of senile dementia. |
| FB07759 | Fenoldopam | 67227-56-9 | Fenoldopam is a drug and synthetic benzazepine derivative which acts as a selective D1 receptor partial agonist. |
| FB02111 | Dopamine | 51-61-6 | Dopamine is one of the phenethylamine and catecholamine neurotransmitters critical to the extrapyramidal system, the movement and the experience of pleasure and desire. |
| FB07324 | Dopamine HCl | 62-31-7 | Dopamine HCl works as a catecholamine neurotransmitter and a dopamine receptors agonist. It can treat various types of shock clinically. |
| FB09059 | Dexpramipexole | 104632-28-2 | Dexpramipexole is a neuroprotective agent and weak non-ergoline dopamine agonist. |
| FB01587 | Cariprazine HCl | 1083076-69-0 | Cariprazine HCl is an antipsychotic drug candidate that exhibits high selectivity and affinity to dopamine D3 (Ki=0.09 nM) and D2 (Ki=0.5 nM) receptors and moderate affinity to serotonin 5-HT(1A) receptors. |
| FB08914 | Cariprazine | 839712-12-8 | Cariprazine exhibits high selectivity and affinity to dopamine D3 receptor (Ki=0.09 nM) and lower binding activity to dopamine D2 receptor and 5-HT(1A) with Ki of 0.5 nM and 2.6 nM repectively. It has been used as antipsychotics in the treatment of schizophrenia and bipolar disorder. |
| FB10740 | Cabergoline | 81409-90-7 | Cabergoline, an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. |
| FB02596 | Azaperone | 1649-18-9 | Azaperone functions as a dopamine antagonist that can bind to D1 and D2 receptors. It has the characteristics of antihistamines and anticholinergics. |