TNF-alpha
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB12101 | TNF-α-IN-1 | 444287-49-4 | TNF-α-IN-1 is a TNF-α inhibitor extracted from patent US20030096841A1, compound example I-7. |
| FB00112 | Thalidomide | 50-35-1 | Thalidomide targets to CRBN with IC50 of 8.5 nM. It can inhibit biosynthesis of TNF-α and has anti-angiogenic and immunosuppressive effects. |
| FB15232 | S-99 | 1124381-69-6 | S-99 is an inhibitor of LPS-induced TNFalpha release. |
| FB03433 | Roquinimex | 84088-42-6 | Roquinimex is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity and inhibits angiogenesis and reduces the secretion of TNF alpha. |
| FB11564 | R-7050 | 303997-35-5 | R-7050 is an antagonist of tumor necrosis factor receptor (TNFR) that towards TNFα. |
| FB01700 | QNZ | 545380-34-5 | QNZ can inhibit the activation of NF-κB and the production of TNF-α with IC50 of 11 nM and 7 nM, respectively. |
| FB03415 | Pomalidomide | 19171-19-8 | Pomalidomide can inhibit LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. |
| FB07411 | Nedocromil Sodium | 69049-74-7 | Nedocromil Sodium is a potent TNF-α inhibitor with an IC50 value of 1.67 μM for Blood eosinophils. |
| FB06845 | Necrostatin 2 S-Enantiomer | 852391-20-9 | Necrostatin 2 S enantiomer is a potent necroptosis inhibitor with EC50 of 50 nM. |
| FB06844 | Necrostatin 2 | 852391-19-6 | Necrostatin 2 is a potent necroptosis inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. |
| FB07785 | Necrostatin 2 Racemate | 852391-15-2 | Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM. |
| FB03372 | Lenalidomide | 191732-72-6 | Lenalidomide, a analog of thalidomide, is TNF-α secretion inhibitor with IC50 of 13 nM. |
| FB03372 | Lenalidomide | 191732-72-6 | Lenalidomide, a analog of thalidomide, is TNF-α secretion inhibitor with IC50 of 13 nM. |
| FB02408 | Lenalidomide HCl | 1243329-97-6 | Lenalidomide is a TNF-α secretion inhibitor with IC50 of 13 nM. |
| FB06834 | Lenalidomide Hemihydrate | 847871-99-2 | Lenalidomide is a potent inhibitor of TNF-α and has antiangiogenic effect. |
| FB03939 | GSK481 | 1622849-58-4 | GSK'481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cells. |
| FB05453 | Grandifloroside | 61186-24-1 | Grandifloroside, a natural product isolated and purified from the branch of Emmenopterys henryi Oliv. |
| FB08911 | Forsythoside B | 81525-13-5 | Forsythoside B is a natural product isolated and purified from the fruits of Forsythia suspensa which inhibits inflammatory response,and has antioxidant properties with potent neuroprotective effects with a favorable therapeutic time-window, reduce of cerebral ischemia and reperfusion injury degree, attenuating blood-brain barrier (BBB) breakdown, and can rescue cardiac function from I/R injury. |
| FB02761 | DCVC | 13419-46-0 | DCVC E-isomer inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro. |
| FB10023 | C 87 | 332420-90-3 | C 87 is a small-moleculeTNFα inhibitor and potently inhibits TNFα-induced cytotoxicity with an IC50 of 8.73 μM. |
| FB07022 | Butoconazole Nitrate | 64872-77-1 | Butoconazole nitrate is an anti-fungal agent and the IC50s of IL-2, TNFα, IFN and GM-CSF are 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively. |
| FB01591 | Bioymifi | 1420071-30-2 | Bioymifi is an activatior of the TRAIL receptor DR5 in cancer cells. |
| FB01652 | 14-Deoxyandrographolide | 4176-97-0 | 14-Deoxyandrographolide, a natural product isolated and purified from the herbs of Andrographis paniculata (Burm. |
| FB18062 | (Rac)-Benpyrine | 1333714-43-4 | (Rac)-Benpyrine is the racemate form of Benpyrine. Benpyrine could directly bind to TNF-α and block TNF-α-trigged signaling activation in vitro and in vivo. Administration of benpyrine by gavage significantly relieved the symptoms of collagen-induced arthritis and imiquimod-induced psoriasiform inflammation in mice. |