Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB19612 | PROTAC Mcl1 degrader-1 | 2163793-38-0 | PROTAC Mcl1 degrader-1 (compound C3) is a PROTAC targeting on Bcl-2 and Mcl-1 with DC50 values of 3μM and 0.7μM, respectively. |
| FB19685 | PROTAC Bcl2 degrader-1 | 2378801-85-3 | PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC targeting on Bcl-2 and Mcl-1 with DC50 values of 3μM and 0.7μM, respectively. |