IRE1
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB04878 | STF-083010 | 307543-71-1 | STF-083010 is a potent IRE1α endonuclease inhibitor which can block endogenous XBP1 mRNA splicing. |
| FB15256 | MKC8866 | 1338934-59-0 | MKC8866 is an inositol requiring enzyme 1 (IRE-1α) inhibitor with IC50＜0.1 μM. |
| FB09907 | MKC3946 | 1093119-54-0 | MKC3946 is a small-molecule IRE1α endoribonuclease domain inhibitor which can block XBP1 splicing. |
| FB02644 | KIRA6 | 1589527-65-0 | In INS-1 cells, KIRA6 inhibits IRE1α auto-phosphorylation by Tg and XBP1 mRNA splicing by Tm in a dose-dependent manner. |
| FB02368 | APY29 | 1216665-49-4 | APY29 is an allosteric modulator of IRE1α and inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity. |