Glucagon Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17637 | Teduglutide | 197922-42-2 | Teduglutide , an analog of glucagon-like peptide 2, improves intestinal rehabilitation by promoting mucosal growth and possibly by inhibiting gastric emptying and secretion, which in turn reduces intestinal losses and promotes intestinal absorption. |
| FB10300 | Taspoglutide | 275371-94-3 | Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist developed for treatment of type 2 diabetes, with an EC50 value of 0.06 nM. |
| FB17226 | Skyrin | 602-06-2 | Skyrin is a fungal bisanthroquinone. It exhibits functional glucagon antagonism by uncoupling the glucagon receptor from adenylate cyclase activation in rat liver membranes. |
| FB11556 | Semaglutide | 910463-68-2 | Semaglutide is an analog of human GLP-1 with long-acting effect over the other GLP-1Ras. |
| FB16363 | PF-06882961 | 2230198-02-2 | PF-06882961 is a potent and orally bioavailable GLP-1R agonist. |
| FB06331 | Octreotide Acetate(Random Configuration) | 760176-26-9 | Octreotide is used to treat severe watery diarrhea and sudden reddening of the face and neck caused by certain types of tumors. |
| FB09244 | MK-0893 | 870823-12-4 | MK 0893 is a potent, selective glucagon receptor antagonist with IC50 of 6.6 nM, showing > 200 fold selectivity for GIPR, PAC1, GLP-1R, VPAC1 and VPAC2. |
| FB15326 | Lixisenatide | 320367-13-3 | Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). |
| FB03436 | Liraglutide | 204656-20-2 | Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus. |
| FB15294 | LGD6972 | 1207989-09-0 | LGD-6972 is a novel and orally-available glucagon receptor antagonist used to treat type 2 diabetes mellitus in Phase 1 study. |
| FB12339 | L-168,049 | 191034-25-0 | L-168,049 is a very potent and selective, non-competitive antagonist of the human glucagon receptor with IC50 of 3.7 nM. |
| FB10296 | GRA Ex-25 | 307983-31-9 | GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively. |
| FB00368 | Glucagon Receptor Antagonists-4 | 1393124-08-7 | Glucagon receptor antagonists-4 is an selective antagonist of glucagon receptor. |
| FB04064 | Glucagon Receptor Antagonists-3 | 202917-17-7 | Glucagon receptor antagonists-3 is a highly potent glucagon receptor antagonist. |
| FB04065 | Glucagon Receptor Antagonists-2 | 202917-18-8 | Glucagon receptor antagonists-2 is a highly potent glucagon receptor antagonist. |
| FB03067 | Glucagon Receptor Antagonists-1 | 503559-84-0 | Glucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist. |
| FB10299 | GLP-1(7-37) | 106612-94-6 | GLP-1(7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1(1-37). |
| FB09185 | Exendin-4 | 141758-74-9 | Exendin-4 is a high affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM) and originally isolated from Heloderma suspectum venom. |
| FB10637 | Exendin-4 Acetate | 914454-01-6 | Exendin-4 acetate is a 39 amino acid peptide, activates GLP-1 (glucagon-like peptide-1) receptors to increase intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. |
| FB12131 | Albiglutide | 782500-75-8 | Albiglutide is a recombinant fusion protein consisting of two copies of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36), modified with a glycine substituted for the naturally occurring alanine at position 8 in order to augment resistance to DPP-4. |
| FB01043 | Adomeglivant | 1488363-78-5 | Adomeglivant is a potent and selective glucagon receptor antagonist that is used in clinical trial for type 2 diabetes mellitus. |