Opioid Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB09614 | [D-Ala2]Leucine-Enkephalin | 64963-01-5 | [D-Ala2]Leucine-Enkephalin is a potent, long-acting Leu-enkephalin analog agonist of delta opioid receptor. |
| FB11014 | TRV0109101 | 1401027-29-9 | TRV0109101, a G protein-biased agonist of the µ-opioid receptor, which may be an effective therapeutic avenue for managing chronic pain with reduced propensity for opioid-induced hyperalgesia. |
| FB11015 | TRV0109101 HCl | 2101210-22-2 | TRV0109101 HCl, a G protein-biased agonist of the µ-opioid receptor, which may be an effective therapeutic avenue for managing chronic pain with reduced propensity for opioid-induced hyperalgesia. |
| FB03157 | TRV 130 Racemate | 1401028-25-8 | TRV 130 racemate is the racemate form of TRV130, which a μ-opioid receptor (MOR) G protein-biased ligand. |
| FB03156 | TRV 130 | 1401028-24-7 | TRV 130 is a μ-opioid receptor (MOR) G protein-biased ligand and elicits robust G protein signaling (pEC50=8.1), with potency and efficacy similar to morphine, but with far less β-arrestin recruitment and receptor internalization. |
| FB08344 | TRV 130 HCl | 1401031-39-7 | TRV 130 HCl is a μ-opioid receptor (MOR) G protein-biased ligand and elicits robust G protein signaling (pEC50=8.1), with potency and efficacy similar to morphine, but with far less β-arrestin recruitment and receptor internalization. |
| FB00127 | Trimebutine Maleate | 34140-59-5 | Trimebutine Maleate is an agonist effect on peripheral μ, k and δ opiate receptors, and also shows antimuscarinic effect. |
| FB00505 | Trimebutine | 39133-31-8 | Trimebutine is an agonist effect on peripheral μ, k and δ opiate receptors, and also shows antimuscarinic effect. |
| FB11611 | PZM-21 | 1997387-43-5 | PZM21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM. |
| FB12062 | ORL1 Antagonist 1 | 1174985-59-1 | ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM. |
| FB07203 | Naltrexone HCl | 16676-29-2 | Naltrexone HCl is an antagonist of μ-opioid receptor. |
| FB07201 | Naloxone | 465-65-6 | Naloxone is a medication used to block the effects of opioids, especially in overdose. |
| FB07202 | Naloxone HCl 2H2O | 51481-60-8 | Naloxone HCl is an opioid inverse agonist drug used to counter the effects of opiate overdose. |
| FB09662 | Naloxone HCl | 357-08-4 | Naloxone HCl is a competitive opioid receptor antagonist. |
| FB02790 | Naloxegol Oxalate | 1354744-91-4 | Naloxegol oxalate is a CYP3A4 enzyme inhibitor, is a peripherally-selective opioid antagonist, for the treatment of opioid-induced constipation. |
| FB06847 | Naloxegol | 854601-70-0 | Naloxegol is both a peripherally selective opioid receptor antagonist and a CYP3A4 enzyme inhibitor. |
| FB07142 | Nalmefene HCl | 58895-64-0 | Nalmefene HCl, originally known as nalmetrene, is an opioid antagonist,used primarily in the management of alcohol dependence. It has also been investigated for the treatment of other addictions such as pathological gambling. |
| FB07407 | N-Desmethylclozapine | 6104-71-8 | N-Desmethylclozapine is a dengue virus inhibitor, and an agonist of δ-opioid receptor. |
| FB02600 | Met-Enkephalin | 58569-55-4 | Met-enkephalin is an Opioid related peptide work as a potent agonist of the δ-opioid receptor, and to a lesser extent the μ-opioid receptor, with little to no effect on the κ-opioid receptor. |
| FB04121 | Meptazinol HCl | 59263-76-2 | Meptazinol HCl is both a partial agonist of μ1 opioid receptor and an AChE inhibitor. |
| FB02262 | MCOPPB triHCl | 1108147-88-1 | MCOPPB 3HCl is a nociceptin receptor agonist with pKi of 10.07, displaying weaker activity at other opioid receptors. |
| FB02767 | LY2795050 | 1346133-08-1 | LY2795050 is a selective κ-opioid Receptor (KOR) antagonist (IC50=0.72 nM) and has the potential as a PET tracer to image KOR in vivo. |
| FB11037 | LY2444296 | 1346133-11-6 | LY2444296 is a short-acting kappa opioid receptor antagonist. |
| FB15225 | LY-2940094 Tartrate | 1307245-87-9 | LY-2940094 tartrate is the tartrate form of LY-2940094 which is an antagonist of nociceptin receptor that is used for the treatment of major depressive disorder and alcoholism. |
| FB00490 | LY2456302 | 1174130-61-0 | LY-2456302 is a potent and centrally-penetrant kappa opioid receptor antagonist with a Ki of 0.807 nM. |
| FB03555 | Loperamide | 53179-11-6 | Loperamide is a medication used to decrease the frequency of diarrhea. |
| FB03556 | Loperamide HCl | 34552-83-5 | Loperamide HCl is a potent and selective μ-opioid receptor agonist. |
| FB04592 | JTC-801 | 244218-51-7 | JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, and weakly inhibits receptors δ, κ, and μ. |
| FB03407 | JDTic | 361444-66-8 | JDTic is a highly selective antagonist for the κ-opioid receptor and without affecting the μ- or δ-opioid receptors. |
| FB06288 | JDTic 2HCl | 785835-79-2 | JDTic 2HCl is a highly selective antagonist for the κ-opioid receptor without affecting the μ- or δ-opioid receptors. |
| FB00089 | GSK-1521498 | 1007573-18-3 | GSK-1521498 is a μ-opioid receptor antagonist. It has been shown to attenuate reward-driven compulsive behaviours, such as stimulant drug seeking or binge eating, in animals and humans. |
| FB01415 | Ethoheptazine | 77-15-6 | Ethoheptazine is an opioid analgesic from the phenazepane family. |
| FB16861 | Desmethylcarfentanil acid | 186022-53-7 | Desmethylcarfentanil acid could be developed as a PET agent for the non-invasive study of µ opioid receptors in the brain. |
| FB00193 | DAMGO | 78123-71-4 | DAMGO is a highly selective peptide agonist for the μ opioid receptor. |
| FB02599 | DADLE | 63631-40-3 | DADLE ([D-Ala2, D-Leu5]-Enkephalin) is a water soluble Opioid Receptor peptide agonist. |
| FB10100 | Cebranopadol (1α,4α)stereoisomer | 863513-93-3 | Cebranopadol(1α,4α)stereoisomer is a stereoisomer of cebranopadol. |
| FB08267 | Cebranopadol | 863513-91-1 | Cebranopadol is an analgesic NOP and opioid receptor agonist with Kis/EC50s of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, 18 nM/110 nM for human NOP, MOP, KOP and delta-opioid peptide (DOP) receptor, respectively. |
| FB16638 | BRL 52537 hydrochloride | 112282-24-3 | BRL-52537 hydrochloride is a potent and highly selective κ-opioid agonist. It has neuroprotective effects in animal studies, and is used for research into potential treatments for stroke and heart attack as well as more general brain research. |
| FB17910 | Bevenopran | 676500-67-7 | Bevenopran is a peripheral μ-opioid receptor antagonist. |
| FB03159 | BAN ORL 24 | 1401463-54-4 | BAN ORL 24 is a potent and selective NOP receptor antagonist. (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). |
| FB13025 | AR-M 1000390 HCl | 209808-47-9 | AR-M 1000390 HCl is a non-peptidic and low-internalizing δ-selective opioid receptor agonist. |
| FB08757 | Alvimopan | 156053-89-3 | Alvimopan is a peripherally selective opioid mu receptor antagonist. |
| FB02822 | Alvimopan Monohydrate | 1383577-62-5 | Alvimopan is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
| FB03353 | Alvimopan Dihydrate | 170098-38-1 | Alvimopan is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. |
| FB05307 | Akuammigine | 642-17-1 | Akuammidine, a natural product isolated and purified from the herbs of Picralima nitida with in vitro antimalarial activity, shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 mM at mu-, delta- and kappa-opioid binding sites, respectively and the agonist actions of akuammidine in the mouse-isolated vas deferens were antagonised by naloxone and the mu-opioid receptor selective antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) confirming an action at mu-opioid receptors, and competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. |
| FB05362 | ADL-5859 HCl | 850173-95-4 | ADL-5859 HCl is both a δ-opioid receptor agonist (Ki=0.84 nM, EC50=20 nM) and selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel with IC50 value of 78 µM. |
| FB02218 | (-)-Naltrexone | 16590-41-3 | (-)-Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. |
| FB03462 | (-)-Menthol | 2216-51-5 | (-)-Menthol is a natural product obtained from the oils of corn mint, peppermint, or other mints, as a weak kappa opioid receptor agonist. It has local anesthetic and counterirritant qualities, and used to relieve minor throat irritation. |
| FB08445 | (+)-Matrine | 519-02-8 | (+)-Matrine is a naturally occuring κ-opioid and μ-opioid receptor agonist. |
| FB20341 | SNC 80 | 156727-74-1 | Highly selective non-peptide δ agonist |