Androgen Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB11727 | YK11 | 1370003-76-1 | YK11 is a partial agonist of androgen receptor, with osteogenic activity. |
| FB00417 | Trenbolone Acetate | 10161-34-9 | Trenbolone acetate is a synthetic androgen steroid with anabolic properties. |
| FB03845 | trans-Androsterone | 481-29-8 | Trans-Androsterone is a naturally produced steroid hormone with weak androgenic activity. |
| FB00025 | Testosterone Propionate | 57-85-2 | Testosterone propionate is an efficient androgenic hormone for the treatment of low testosterone. |
| FB09792 | Testosterone | 58-22-0 | Testosterone is a steroid hormone from the androgen group and is found in mammals, reptiles, birds and other vertebrates. |
| FB00024 | Testosterone Hydrocinnamate | 1255-49-8 | Testosterone hydrocinnamate, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester-specifically, the C17β phenylpropionate ester of testosterone. |
| FB04217 | Spironolactone | 52-01-7 | Spironolactone is a competitive inhibitor of androgen receptor with IC50 of 7.1 nM. |
| FB03223 | RU 58841 | 154992-24-2 | RU 58841 is a nonsteroidal antiandrogen for potential use as a topical treatment for androgen-dependent conditions including acne, pattern hair loss, and excessive hair growth. |
| FB01574 | RD 162 | 915087-27-3 | RD 162 is an orally active and very potent antagonist of androgen receptor (AR) and is a second-generation of antiandrogen for the treatment of advanced prostate cancer and highly recommended tool in AR research. |
| FB17889 | Ralaniten triacetate | 1637573-04-6 | Ralaniten triacetate (EPI-506), the pro-drug of Ralaniten, is a first-in-class, orally active androgen receptor (AR) N-terminal domain (NTD) inhibitor. Ralaniten triacetate shows activity against both full length and resistance-related AR species, including AR-v7. |
| FB02315 | RAD140 | 1182367-47-0 | RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). |
| FB17820 | Prochloraz | 67747-09-5 | Prochloraz is an imidazole antifungal that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. Prochloraz inhibits human placenta microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an antagonist of the estrogen receptor (ER) and androgen receptor (AR) (IC50s = 25 μM and 4 μM, respectively) as well as activates the aryl hydrocarbon receptor (AhR; EC50 = 1 μM). |
| FB07950 | Oxendolone | 33765-68-3 | Oxendolone is a steroidal antiandrogen and progestin of the 19-nortestosterone group. |
| FB01242 | Ostarine | 841205-47-8 | Ostarine is a selective androgen receptor modulator (SARM) with Ki of 3.8 nM, and is tissue-selective for anabolic organs. |
| FB02712 | ORM-15341 | 1297537-33-7 | ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. |
| FB02713 | ODM-201 | 1297538-32-9 | ODM-201 is a competitive inhibitor of androgen receptor with IC50 value of 26 nM and inhibits AR nuclear translocation with Ki value of 11 nM. |
| FB06751 | Nomegestrol | 58691-88-6 | Nomegestrol is a steroidal progestin. |
| FB10594 | Nilutamide | 63612-50-0 | Nilutamide is a non-steroidal androgen receptor antagonist and also inhibits androgen biosynthesis in vitro. |
| FB07133 | Nadolol | 42200-33-9 | Nadolol is a new beta-adrenoceptor blocking agent without intrinsic sympathomimetic action and with an extremely long plasma half life. Nadolol antagonizes isoproterenol-induced tachycardia and ouabain-induced arrhythmias in cats, antagonizes coronary artery ligation-induced ventricular fibrillation and suppresses ventricular ectopic activity during vagal stimulation in dogs. |
| FB02406 | N-desmethyl Enzalutamide | 1242137-16-1 | N-Desmethyl enzalutamide is a major metabolite of Enzalutamide, Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM. |
| FB06213 | MK-0773 | 606101-58-0 | MK-0773, one of selective androgen receptor modulators (SARMs), is a 4-aza-steroid that exhibited tissue selectivity in humans (IC50= 6.6 nM). |
| FB03911 | Megestryl Acetate | 595-33-5 | Megestryl Acetate is a synthetic progesterone analog. |
| FB06330 | LGD-4033 | 1165910-22-4 | LGD-4033 is a nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity. |
| FB01721 | Hydroxyflutamide | 52806-53-8 | Hydroxyflutamide is a derivative of the synthetic steroid ethisterone, that suppresses the production of gonadotrophins, and has some weak androgenic effects. |
| FB02630 | Hydromadinone | 16469-74-2 | Hydromadinone, is a steroidal progestin of the 17α-hydroxyprogesterone group. |
| FB02575 | GSK2881078 | 1539314-06-1 | GSK 2881078 is a selective androgen receptor modulator potentially for the treatment of cachexia. |
| FB02366 | GLPG0492 R-Enantiomer | 1215085-93-0 | GLPG0492 R-enantiomer is the R-Enantiomer of GLPG-0492, which is a selective androgen receptor modulator. |
| FB02365 | GLPG0492 | 1215085-92-9 | GLPG0492 is a selective androgen receptor modulator and exhibits anabolic activity on muscle, strongly dissociated from the androgenic activity on prostate after oral dosing. |
| FB02089 | Gestonorone | 2137-18-0 | Gestronol is a steroidal progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups. |
| FB03734 | Flutamide | 13311-84-7 | Flutamide is a competitive non-steroidal antagonist of androgen receptor. |
| FB08487 | EPI-001 | 227947-06-0 | EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ∼6 μM and a selective PPAR-gamma modulator. |
| FB03818 | Enzalutamide | 915087-33-1 | Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. |
| FB07796 | DHEA | 53-43-0 | DHEA is an endogenous steroid hormone acting as both an androgen receptor antagonist and an estrogen receptor agonist. |
| FB03404 | Dehydroisoandrosterone 3-Acetate | 853-23-6 | Dehydroisoandrosterone 3-Acetate is an endogenous steroid hormone acting as both an androgen receptor antagonist and an estrogen receptor agonist. |
| FB00138 | Cyproterone Acetate | 427-51-0 | Cyproterone Acetate is an antagonist and partial agonist of androgen receptor with IC50 value of 7.1 nM and EC50 value of 4μM. |
| FB04051 | Cortexolone 17 alpha-Propionate | 19608-29-8 | Cortexolone 17 alpha-propionate is a topical and peripherally selective androgen antagonist, which is used in treatment of acne and androgenic alopecia. |
| FB02642 | Boldenone Undecylenate | 13103-34-9 | Boldenone undecylenate is a synthetic steroid which has a similar effect as the natural steroid testosterone. |
| FB08475 | BMS-564929 | 627530-84-1 | BMS-564929 is an androgen receptor (AR) agonist, binds to androgen receptor (AR) with a Ki of 2.11±0.16 nM. |
| FB06549 | Bicalutamide | 90357-06-5 | Bicalutamide is non-steroidal androgen receptor antagonist with IC50 value of 190 nM. |
| FB01116 | AZD3514 | 1240299-33-5 | AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression. |
| FB08154 | Dimethylcurcumin | 52328-98-0 | ASC-J9, an antitumor agent, suppresses castration-resistant prostate cancer growth via degradation of full-length and splice variant androgen receptors. |
| FB18902 | ARV-110 | 2222112-77-6 | ARV-110 is an orally active, specific androgen receptor PROTAC degrader with DC50 < 1nM. |
| FB00860 | Apalutamide | 956104-40-8 | ARN-509 can compeitively and selectively inhibit androgen receptor with IC50 value of 16 nM. |
| FB10818 | Androgen Receptor Modulator C7 | 2109805-69-6 | Androgen receptor modulator C7 is a potent AR (ARE EC50 = 0.34 nM) and tissue-selective (N/C interaction EC50 = 1206 nM) modulator. |
| FB06661 | Andarine | 401900-40-1 | Andarine is an oral-available and selective non-steroidal androgen receptor agonist with Ki value of 4 nM. |
| FB11951 | ACP-105 | 899821-23-9 | ACP-105 is a potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone. |
| FB02473 | 3,3'-Diindolylmethane | 1968-05-4 | 3,3'-Diindolylmethane is an AR structurally similar androgen receptor antagonist. |
| FB12875 | 1-Phenylpentan-1-ol | 583-03-9 | 1-Phenylpentan-1-ol is an intermediate for synthesis of β-amino-carbonyl-based androgen receptor antagonist. |
| FB09528 | Dihydrotestosterone | 521-18-6 | |
| FB09793 | Testosterone Enanthate | 315-37-7 |