| FB12956 |
H-DL-Nva-OH
|
760-78-1 |
H-DL-Nva-OH is the derivative of L-norvaline which is an inhibitor of arginase. |
| FB10915 |
CB-1158
|
1345810-21-0 |
CB-1158 is a potent arginase inhibitor. CB-1158 has the potential for anti-tumor activity in renal cell cancer, breast cancer, non-small cell lung cancer, acute myeloid leukemia, and other tumor types where arginase-secreting MDSCs are known to play an immunosuppressive role. |
| FB11937 |
CB-1158 HCl
|
N/A |
CB-1158 HCl is a potent and orally bioavailable inhibitor of arginase, with IC50s of 86 and 296 nM for recombinant human arginase 1 and 2, respectively. |
| FB09869 |
BEC HCl
|
222638-67-7 |
BEC HCl is a competitive arginase inhibitor with Ki of 0.31 μM and 0.4-0.6 μM for Arginase II and rat Arginase I respectively. |
| FB02765 |
Arginase Inhibitor 1
|
1345808-25-4 |
Arginase inhibitor 1 is a potent small molecule inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. |