The FMS-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD) is one of the most frequent mutations found in acute myeloid leukemia (AML) patients, with a frequency of 20–30%.
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
FB19633 | PROTAC FLT-3 degrader 1 | 2230826-81-8 | PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction. |