The FMS-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD) is one of the most frequent mutations found in acute myeloid leukemia (AML) patients, with a frequency of 20–30%.

FLT3-ITD/PROTAC

货号 产品名 CAS号 信息
FB19633 PROTAC FLT-3 degrader 1 2230826-81-8 PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction.
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