Phospholipase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB15380 | VU-0155069 | 1130067-06-9 | VU-0155069 is a selective phospholipase D1 (PLD1) inhibitor with IC50 values of 46 and 933 nM for PLD1 and PLD2 respectively. |
| FB00881 | Varespladib | 172732-68-2 | Varespladib is a potent and selective human non-pancreatic secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM. |
| FB00048 | U-73122 | 112648-68-7 | U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO(5-lipoxygenase). |
| FB17919 | trans-Benzylideneacetone | 1896-62-4 | trans-Benzylideneacetone (trans-Benzalacetone), a metabolite of gram-negative entomopathogenic bacterium Xenorhabdus nematophila, is an enzyme inhibitor against phospholipase A2 (PLA2). trans-Benzylideneacetone is an immunosuppressant. |
| FB02256 | SPK-601 | 1096687-52-3 | SPK-601 is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor and is a useful antimicrobial agent. |
| FB15229 | N-(p-amylcinnamoyl) Anthranilic Acid | 110683-10-8 | N-(p-amylcinnamoyl) Anthranilic Acid is a PLA2 inhibitor and TRP channel modulator. |
| FB10074 | ML348 | 899713-86-1 | ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases. |
| FB16543 | ML 349 | 890819-86-0 | ML 349 is a selective and reversible lysophospholipase 2 (LYPLA2) inhibitor with IC50 of 144 nM. |
| FB15375 | Mepacrine | 83-89-6 | Mepacrine is an acridine derivative formerly widely used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It's also an inhibitor of phospholipase A2. |
| FB08882 | Mepacrine 2HCl | 69-05-6 | Mepacrine 2HCl is an acridine-derived yellow dye, previously used in the therapy and prevention of malaria and later as an antiprotozoal and immunomodulatory agent. It's also an inhibitor of phospholipase A2. |
| FB08883 | Mepacrine 2HCl 2H2O | 6151-30-0 | Mepacrine 2HCl 2H2O is an acridine derivative formerly widely used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It's also an inhibitor of phospholipase A2. |
| FB17571 | m-3M3FBS | 200933-14-8 | m-3M3FBS is a novel phospholipase C activator. It can be developed as a novel anti-leukemic agent. |
| FB08422 | FIPI | 939055-18-2 | FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM) preventing PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. |
| FB07224 | Darapladib | 356057-34-6 | Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. |
| FB00152 | D609 Potassium Salt | 83373-60-8 | D609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM) and antiviral and antitumor agent. |
| FB02391 | CAY10650 | 1233706-88-1 | CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. |
| FB18251 | CAY10594 | 1130067-34-3 | CAY10594 is a selective PLD2 inhibitor with IC50 values of 140nM and 5.1μM for PLD2 and PLD1, respectively. It strongly inhibits the invasive migration of breast cancer cells in transwell assays. |
| FB17703 | 7,7-Dimethyleicosadienoic Acid | 89560-01-0 | 7,7-Dimethyleicosadienoic Acid is a selective secretory type phospholipase A2 (PLA2) inhibitor with IC50 value of 250μM in the presence of Epo. |
| FB20381 | Edelfosine | 77286-66-9 | Selective PI-PLC inhibitor, also PAF receptor agonist |