| FB07405 |
Sardomozide 2HCl
|
138794-73-7 |
Sardomozide 2HCl is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. |
| FB20275 |
Mitoguazone
|
459-86-9 |
Mitoguazone is a guanylhydrazone with potential antineoplastic activity. Mitoguazone competitively inhibits S-adenosyl-L-methionine decarboxylase (SAMD), an enzyme involved in the synthesis of polyamines, resulting in decreased proliferation of tumor cells, antimitochondrial effects, and p53-independent apoptosis. Polyamines, specifically spermine and spermidine, are essential for thymidine kinase production, DNA synthesis, and cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). |
| FB16885 |
JZP 430
|
1672691-74-5 |
JZP 430 is an irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 value of 44 nM. |
| FB00455 |
Adenosine Dialdehyde
|
34240-05-6 |
Adenosine dialdehyde (AdOx), an indirect inhibitor that can be incorporated by cells. |
| FB10431 |
3-Deazaadenosine
|
6736-58-9 |
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM; has anti-inflammatory, anti-proliferative and anti-HIV activity. |