Caspase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB10217 | Z-VAD-FMK | 161401-82-7 | Z-VAD-FMK is an irreversible pan-caspase inhibitor. |
| FB08704 | Z-VAD(OMe)-FMK | 187389-52-2 | Z-VAD(OMe)-FMK is a cell-permeable, irreversible broad-spectrum caspase inhibitor, blocks all features of apoptosis. |
| FB00872 | Z-IETD-FMK | 210344-98-2 | Z-IETD-FMK is a specific Caspase-8 inhibitor. |
| FB04078 | Z-DEVD-FMK | 210344-95-9 | Z-DEVD-FMK (1–200 μM) inhibits D4-GDI cleavage and apoptosis in a concentration-dependent manner. |
| FB08340 | VX-765 | 273404-37-8 | VX-765 is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM in a cell-free assay. |
| FB17900 | Taurodeoxycholic acid sodium hydrate | 110026-03-4 | Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid sodium hydrate is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis. |
| FB00621 | Q-VD-Oph | 1135695-98-5 | Q-VD-OPh is a potent pan-caspase inhibitor of caspases 1, 3, 8, and 9 with IC50 values of 50, 25, 100, and 430 nM, respectively, showing inhibitory effects on terminal caspase activation, substrate cleavage, and DNA ladder formation associated with apoptosis. |
| FB08791 | PAC-1 | 315183-21-2 | PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM which activate procaspase-3 to caspase-3 and induces apoptotic death in cancer cells in culture and in mouse xenograft models. |
| FB12057 | ML132 | 1230628-71-3 | ML132 is a potent and selective caspase 1 inhibitor with an IC50 of 0.316 nM. |
| FB10620 | Ginsenoside Rh2 | 78214-33-2 | Ginsenoside Rh2, a natural product isolated and purified from the roots of Panax ginseng C. |
| FB02490 | Emricasan | 254750-02-2 | Emricasan, also called IDN-6556 or PF-03491390, is an inhibitor of activated caspases, and it has sub- to nanomolar activity in vitro. |
| FB06226 | BOC-D-FMK | 634911-80-1 | BOC-D-FMK is a pan-caspase inhibitor. |
| FB10068 | AS101 | 106566-58-9 | AS101 is a potent Caspase-1 inhibitor which can inhibit IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release through Caspase, performing as an immunomodulator. |
| FB17647 | AC-YVAD-CMK | 178603-78-6 | Ac-YVAD-CMK is a tetrapeptide ICE inhibitor. |
| FB12773 | Ac-DEVD-CHO | 169332-60-9 | Ac-DEVD-CHO is a potent and specific Caspase-3 inhibitor with Ki of 230 pM. |
| FB16033 | 2-HBA | 131359-24-5 | 2-HBA is a potent inducer of NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1) which can also activate caspase-3 and caspase-10. |