STING
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB15259 | STING ligand-1 | 2365039-41-2 | STING ligand-1 is a lead STING ligand with IC50 of 68 nM for HAQ STING. |
| FB06255 | STING Agonist-1 | 702662-50-8 | STING agonist-1 is a human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. |
| FB17721 | SR-717 | 2375421-09-1 | SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor activity . |
| FB01072 | ML RR-S2 CDA | 1638241-89-0 | ML RR-S2 CDA is a highly active cyclic-di-nucleotide immune stimulators that activate DCs via the cytoplamtic receptor STING (Stimulator of Interferon Genes). |
| FB10314 | ML RR-S2 CDA Ammonium | 1638750-96-5 | ML RR-S2 CDA ammonium is an inducer of STING (stimulator of interferon genes). ML RR-S2 CDA has enhanced binding affinity to STING and activate all known human STING alleles. |
| FB13123 | diABZI STING agonist-1 | 2138498-18-5 | diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. |
| FB18307 | ChX710 | 2438721-44-7 | ChX710 can boost cellular response to cytosolic DNA via STING. It efficiently primed cellular response to transfected plasmid DNA as assessed by potent synergistic effects on IFN-β secretion and ISG expression levels. |
| FB06838 | cGAMP | 849214-04-6 | cGAMP, an endogenous second messenger, can induce the formation of cytokines and promote innate immune response. It also acts as an activator of STING with antitumor activity. |
| FB12356 | CCCP | 555-60-2 | CCCP can inhibit the activation of STING and is widely used as a protonophore uncoupling agent for oxidative phosphorylation. |
| FB12911 | C-178 | 329198-87-0 | C-178 is a STING inhibitor that can block palmitoylation (PMA)-induced clustering of STING. |
| FB12175 | C-176 | 314054-00-7 | C-176 is a STING inhibitor with anti-inflammatory effection. |
| FB13155 | H-151 | 941987-60-6 | 1-(4-Ethylphenyl)-3-(1H-indol-3-yl)urea, also known as H-151, is a irreversible inhibitor of STING that can inhibit the type I interferon (IFN) response and reduce the phosphorylation of TBK1 and palmitoylation of human STING in vitro. |