CaMK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB10229 | STO-609 | 52029-86-4 | STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase (CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/mL, respectively, and also inhibits their autophosphorylation activities. |
| FB11081 | STO-609 Acetate | 1173022-21-3 | STO-609 acetate is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases (CaMKK) isoforms CaMKKα and CaMKKβ (Ki = 80 and 15 ng/mL, respectively). |
| FB11225 | SMP-114 | 215174-50-8 | SMP-114 is a CaMKII inhibitor with oral bioavailability and mediates the reduction SR Ca(2+) leak and arrhythmogenic cellular correlates. |
| FB01337 | NH125 | 278603-08-0 | NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, also a potent histidine kinase inhibitor. |
| FB04178 | Methophenazine | 388-51-2 | Metofenazate is a selective calmodulin inhibitor. |
| FB09936 | KN-93 Phosphate | 1188890-41-6 | KN-93 Phosphate, a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM, is the water soluble version of KN-93. |
| FB10371 | KN-93 Phosphate(Random Configuration) | 1913269-12-1 | KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| FB03135 | KN-93 | 139298-40-1 | KN-93 is a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM. |
| FB09555 | KN-93 HCl | 1956426-56-4 | KN-93 HCl is a membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. |
| FB01083 | KN-92 Phosphate | 1135280-28-2 | KN-92 phosphate is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| FB10372 | KN-92 | 176708-42-2 | KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| FB03217 | KN-92 HCl | 1431698-47-3 | KN-92 HCl a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
| FB15659 | DDD107498 | 1469439-69-7 | DDD107498 is a multiple-stage antimalarial agent targeting on eEF2. |
| FB12119 | CRT0066101 | 1883545-60-5 | CRT0066101 reduces BrdU incorporation, increases apoptosis, blocks neurotensin (NT)-induced PKD1/2 activation, reduces NT-induced PKD-mediated Hsp27 phosphorylation, attenuates PKD1-mediated NF-κB activation, and abrogates expression of NF-κB-dependent-dependent proliferative and pro-survival proteins. |
| FB12262 | Camstatin | 1002295-95-5 | Camstatin is a calmodulin antagonist. |
| FB02356 | CaMKII-IN-1 | 1208123-85-6 | CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM, displaying significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC. |
| FB12399 | W-5 HCl | 61714-25-8 | Calmodulin antagonist |
| FB12423 | W-13 HCl | 88519-57-7 | Calmodulin antagonist |
| FB12431 | W-9 HCl | 69762-85-2 | Calmodulin antagonist |
| FB12543 | Calmidazolium Chloride | 57265-65-3 | Calmidazolium Chloride is a calmodulin antagonist. |
| FB08189 | Berbamine | 478-61-5 | Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII. |
| FB08190 | Berbamine HCl | 6078-17-7 | Berbamine 2HCl, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII. |
| FB12338 | Autocamtide-2-related Inhibitory Peptide, myristoylated | 201422-04-0 | Autocamtide-2-related Inhibitory Peptide, myristoylated is a CaM kinase II inhibitor that enhances cell permeable derivative of Autocamtide-2-related inhibitory peptide. |
| FB12598 | Autocamtide-2-related Inhibitory Peptide | 167114-91-2 | Autocamtide-2-related Inhibitory Peptide is a selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor with IC50 of 40 nM. |
| FB10842 | Arcyriaflavin A | 118458-54-1 | Arcyriaflavin A is a potent inhibitor of cdk4/cyclin D1 (IC50 = 59 nM) and CaM kinase II (IC50 = 25 nM) but displays selectivity over several other kinases in vitro (IC50 values for inhibition of PKA and PKC are > 2 and > 100 μM respectively). It can also inhibit human cytomegalovirus (HCMV) replication in vitro (IC50 = 200 nM). |
| FB12226 | A-7 HCl | 79127-24-5 | A-7 HCl is a potent calmodulin antagonist. |
| FB12325 | CGS 9343B | 109826-27-9 |