Factor Xa
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB01377 | Rivaroxaban | 366789-02-8 | Rivaroxaban is an inhibitor of factor Xa (FXa) with IC50 of 0.7 nM and Ki of 0.4 nM which developed for the treatment of thrombotic disease. |
| FB04046 | Otamixaban | 193153-04-7 | Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. |
| FB06708 | Fondaparinux Sodium | 114870-03-0 | Fondaparinux sodium is a pentasaccharide inhibitor of antithrombin-dependent factor Xa (IC50 = 40 nM). It can bind to antithrombin III. |
| FB07036 | Edoxaban Tosylate Monohydrate | 1229194-11-9 | Edoxaban tosylate is a selective factor Xa inhibitor with Ki of 0.561 nM, > 10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug. |
| FB08086 | Edoxaban Tosylate | 480449-71-6 | Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. |
| FB09121 | Edoxaban | 480449-70-5 | Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. |
| FB03029 | Betrixaban | 330942-05-7 | Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM (inhibition of Factor 10a). |
| FB02114 | Apixaban | 503612-47-3 | Apixaban is a direct factor Xa inhibitor with an IC50 of 0.08 nM and 0.17 nM in human and rabbit, respectively. |
| FB06870 | 5-R-Rivaroxaban | 865479-71-6 | 5-R-Rivaroxaban is an (R) enantiomer of rivaroxaban, an oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. |