URAT1
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB02785 | Verinurad | 1352792-74-5 | Verinurad is an inhibitor of urate transporter with EC50 of 0.05 μM. |
| FB05931 | Metronidazole | 443-48-1 | Metronidazole is an inhibitor of OAT3 and can inhibit the transport activity of OAT3 with IC50 and Ki of 6.51 ± 0.99 μM, 6.48 μM, respectively. It is also an antibacterial agent for anaerobic bacteria and protozoa. |
| FB02542 | Lesinurad Sodium | 1151516-14-1 | Lesinurad sodium is an inhibitor of URAT1 and OAT and it is also a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively. |
| FB01229 | Lesinurad | 878672-00-5 | Lesinurad is a URAT1 inhibitor with IC50 of 3.5 µM. It acts as a transporter that regulates uric acid excretion in kidney. |