Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity).
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB18231 | PTGR2-IN-22 | 349093-44-3 | PTGR2-IN-1 is a potent PTGR2 inhibitor with IC50 value of ~0.7μM. It increases 15-keto-PGE2-dependent PPARγ transcriptional activity. |