| FB08229 |
β-Melanocyte Stimulating Hormone, Human
|
17908-57-5 |
β-Melanocyte stimulating hormone (MSH) is an agonist of melanocortin-4 receptor. |
| FB15718 |
α-MSH (swine) trifluoroacetate
|
171869-93-5 |
α-MSH is endogenous agonist of melanocortin receptor with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. |
| FB07613 |
α-MSH
|
581-05-5 |
α-MSH is endogenous agonist of melanocortin receptor with Ki values of 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively. |
| FB18029 |
THIQ
|
312637-48-2 |
THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC50=1.2 nM, EC50=2.1 nM) and rMC4R (IC50=0.6 nM, EC50=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants . |
| FB07401 |
Tetracosactide
|
16960-16-0 |
Tetracosactide is a synthetic peptide and analogue of adrenocorticotrophic hormone (ACTH) . |
| FB16462 |
setmelanotide
|
920014-72-8 |
Setmelanotide is a melanocortin 4 receptor agonist. It resulted in substantial and durable reductions in hyperphagia and body weight of severely obese LEPR-deficient individuals over an observation period of 45-61 weeks. It is in phase 3 study for treatment for Leptin Receptor Deficiency Obesity. |
| FB10718 |
Melanotan II
|
121062-08-6 |
Melanotan II, an analog of α-melanocyte stimulating hormone, is agonist of MC3-R/MC4-R melanocortin that induces melanogenesis and thus increases skin pigmentation. |
| FB07398 |
Melanotan I
|
75921-69-6 |
Melanotan I, a synthetic analog of α-MSH, is an agonist of melanocortin receptors with Ki values of 0.085, 0.4, 3.8 and 5.1 nM for MC1, MC3, MC4 and MC5 receptors respectively. |
| FB07435 |
ACTH (11-24)
|
4237-93-8 |
ACTH (11-24), a fragment of adrenocorticotrophin, acts as an antagonist of adrenocorticotropic hormone (ACTH) receptor. |
| FB07402 |
ACTH (1-39), Human
|
12279-41-3 |
ACTH (1-39) is agonist of melanocortin receptor 2 (MC2R) with an EC50 of 57 pM in HeLa cells expressing the mouse receptor. |
| FB15600 |
ACTH (1-39) (mouse, rat)
|
77465-10-2 |
ACTH (1-39) (mouse, rat) is a potent melanocortin 2 (MC2) receptor agonist. |
| FB07400 |
ACTH (1-17)
|
7266-47-9 |
ACTH (1-17), a peptide fragment of adrenocorticotropic hormone, is an agonist of MC1R. It is a |
| FB07399 |
ACTH (1-13)
|
22006-64-0 |
ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone with cytoprotective effects. |
| FB03882 |
ACTH (1-10), Human
|
2791-05-1 |
ACTH (1-10), human is an agonist of melanocortin receptor 3 (MC3R) and MC4R with EC50s of 2.6 and 200 nM, respectively. |