ROS
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17769 | Urolithin C | 165393-06-6 | Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation. |
| FB11168 | U-74389G | 153190-29-5 | U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models. |
| FB09322 | Tiopronin | 1953-02-2 | Tiopronin, derivative of glycine, is used to control the rate of cystine precipitation and excretion. It can be used as an antioxidant agent and radical scavenger. |
| FB17993 | Tempo | 2564-83-2 | Tempo is a classic nitroxide radical and is a selective scavenger of mitochondrial ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects. |
| FB08406 | Piperlongumine | 20069-09-4 | Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and an inhibitor of CRM1 and is also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells. |
| FB04364 | Ophiopogonin D | 945619-74-9 | Ophiopogonin D, a natural product isolated and purified from Radix Ophiopogon japonicus, protects the heart against doxorubicin-induced autophagic injury by reduction of both ROS generation and the disruption of the mitochondrial membrane damage. |
| FB09554 | Oleuropein | 32619-42-4 | Oleuropein is an antioxidant polyphenol isolated from the herb of Olea europaea L.. |
| FB15541 | N-Acetylcysteine amide | 38520-57-9 | N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent, reduces ROS production. |
| FB12879 | L-SelenoMethionine | 3211-76-5 | L-SelenoMethionine is a naturally occurring amino acid and it is one of the important organic selenium sources. |
| FB01557 | Imeglimin | 775351-65-0 | Imeglimin is the first in a tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic β-cells to uniquely target the key defects of type 2 diabetes. |
| FB06283 | Imeglimin HCl | 775351-61-6 | Imeglimin HCl is the first in a tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. |
| FB02845 | Idebenone | 58186-27-9 | Idebenone, a synthetic analog of coenzyme Q10 (CoQ10), can protect mitochondrial membranes against lipid peroxidation and also used as a neuroprotective agent. |
| FB02632 | Hydroquinone | 123-31-9 | Hydroquinone is an inhibitor and antioxidant, also is an intermediate in the synthesis of dyes, motor fuels, and oils. |
| FB07926 | BAPTA | 85233-19-8 | BAPTA is an chelator of Ca2+ that can suppress intracellular reactive oxygen species (ROS). BAPTA is used as a neuroprotective agent. |
| FB06230 | ATN-224 | 649749-10-0 | ATN-224, a copper-chelator agent, can inhibit intracellular SOD1 with IC50 of 17.5 nM. |
| FB09430 | Acetylcysteine | 616-91-1 | Acetylcysteine is an inhibitor of ROS and the production of TNF. It is a pharmaceutical drug and nutritional supplement used as mucolytic agent. |
| FB05188 | 8-Epideoxyloganic Acid | 88668-99-9 | 8-Epideoxyloganic acid, a natural product isolated and purified from the herb of Lamiophlomis rotata, with anti-inflammatory activity, weak antinociceptive activity and bioactivities of analgesia, homeostasis, has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibly through modulation of NOX activity and/or the radical scavenging effect, and beta2 integrin expression in leucocytes. |