PERK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB01533 | ISRIB | 548470-11-7 | trans-ISRIB is an Integrated Stress Response Inhibitor. trans-ISRIB inhibits the eIF2α phosphorylation-mediated unfolded protein response following induction of ER stress (IC50 = 5 nM in a cell-reporter assay). |
| FB09193 | Salubrinal | 405060-95-9 | Salubrinal is a selective inhibitor of eukaryotic translation initiation factor 2 subunit α (eIF2α) dephosphorylation. |
| FB03310 | ISRIB trans-Isomer | 1597403-47-8 | ISRIB is a potent inhibitor of PERK signaling showing inhibition of the ATF4 luciferase reporter in HEK293T cells with IC50 of 5 nM. |
| FB08316 | GSK2656157 | 1337532-29-2 | GSK2656157 is an ATP-competitive inhibitor of PERK enzyme activity with an IC(50) of 0.9 nM and is highly selective for PERK with IC50 values > 100 nM against a panel of 300 kinases. |
| FB08669 | GSK2606414 | 1337531-36-8 | GSK2606414 is an orally available, potent, and selective PERK inhibitor with an IC50 of 0.4 nM. |
| FB08670 | GSK PERK Inhibitor | 1337531-89-1 | GSK PERK inhibitor is a biochemical for proteomics research. |