Myosin
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB00703 | Omecamtiv Mecarbil | 873697-71-3 | Omecamtiv mecarbil is a selective sarcomere-directed cardiac myosin activator with an EC50 of 0.6 μM. |
| FB11326 | MYK-461 | 1642288-47-8 | MYK-461 is a myosin inhibitor potentially for the treatment of hypertrophic cardiomyopathy, and can reduce contractility by decreasing the adenosine triphosphatase activity of the cardiac myosin heavy chain. |
| FB08846 | BTS | 1576-37-0 | BTS is a potent and selective inhibitor of Ca2+-stimulated myosin S1 ATPase with IC50 value of ~5 µM. |
| FB12550 | (R)-(+)-Blebbistatin | 1177356-70-5 | (R)-(+)-Blebbistatin is a selective inhibitor of myosin II ATPase activity. |
| FB01113 | (-)-Blebbistatin | 856925-71-8 | (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5 µM), while poorly inhibiting smooth muscle myosin (IC50 = 80 µM). |