| FB05542 |
Tacrolimus Monohydrate
|
109581-93-3 |
Tacrolimus is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects. Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). |
| FB06770 |
Tacrolimus
|
104987-11-3 |
Tacrolimus is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects. Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). |
| FB01378 |
Pimecrolimus
|
137071-32-0 |
Pimecrolimus is an immunomodulating agent of the calcineurin inhibitor class， effective in various inflammatory skin diseases, including seborrheic dermatitis, cutaneous lupus erythematosus, oral lichen planus, vitiligo and psoriasis. |
| FB00104 |
Cyclosporine
|
79217-60-0 |
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. |
| FB00046 |
Cyclosporine A
|
59865-13-3 |
Cyclosporine A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM. |
| FB12547 |
Calcineurin Autoinhibitory Peptide
|
148067-21-4 |
Calcineurin Autoinhibitory Peptide is a selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) with IC50 ~ 10 μM. |