| FB16922 |
VLX600
|
327031-55-0 |
VLX600 is a novel iron-chelating inhibitor of oxidative phosphorylation, potentiated the effect of radiation in tumor spheroids in a synergistic manner. VLX600 is preferentially active against quiescent cells in colon cancer 3-D microtissues. VLX600 shows enhanced cytotoxic activity under conditions of nutrient starvation and displays tumour growth inhibition in vivo. |
| FB15550 |
S-Gboxin
|
2101317-21-7 |
S-Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. |
| FB00360 |
IACS-010759
|
1570496-34-2 |
IACS-010759 is a potent and selective inhibits oxidative phosphorylation with IC50 < 10 nM. It also binds to and inhibits complex I of the electron transport chain (NADH ubiquinone oxidoreductase), selectively depriving tumor cells of nutrients and energy, inhibiting nucleotide and amino acid production, and induces autophagy. |