Ros1
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17559 | Taletrectinib | 1505515-69-4 | Taletrectinib is a new-generation selective ROS1/Trk Receptor inhibitor with IC50 values of 0.207nM, 0.622nM, 2.28nM and 0.98nM for ROS1, Trk Receptor A, B and C, respectively. It induces dramatic growth inhibition of both wild type and G2032R mutant ROS1-rearranged cancers or NTRK-rearranged cancers in vitro and in vivo. |