| FB02815 |
SR-9009
|
1379686-30-2 |
SR9009 is an agonist of REV-ERBα and REV-ERBβ with IC50 of 670 nM and 800 nM, respectively. |
| FB12693 |
SR 8278
|
1254944-66-5 |
SR8278 is a rev-erbα antagonist. It inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM) and blocks activity of Rev-Erbα agonist GSK 4112 in HEK293 cells. SR8278 increases expression of glucose-regulating genes, G6Pase and PEPCK in HepG2 cells. |
| FB02369 |
GSK4112
|
1216744-19-2 |
GSK4112 is an agonist of Rev-erbα with EC50 of 0.4 μM and it can be designed to mimic the action of heme. |