Lipase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB01488 | XEN445 | 1515856-92-4 | XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM. |
| FB07086 | URB-602 | 565460-15-3 | URB-602 is a selective and non-competitive MAGL with IC50 value of 28 µM (rat brain enzyme). |
| FB03031 | Tanshinone IIA | 568-72-9 | Tanshinone IIA is a naturally occuring cardioprotective agent which can inhibit NF-κB and AP-1 DNA binding and display antioxidant and anti-inflammatory properties. Tanshinone IIA showed inhibitory effect on PL(pro) with IC50 value of 1.6μM and less inhibitory effect on 3CLpro with IC50 value of 89.1μM. |
| FB16532 | RHC 80267 | 83654-05-1 | RHC 80267 is a diacylglycerol (DAG) lipase inhibitor and an important second messenger in signal transduction pathways. |
| FB09770 | Pristimerin | 1258-84-0 | Pristimerin is a natural product isolated and purified from the herb of Tripterygium wilfordii Hook.f. |
| FB07261 | Orlistat | 96829-58-2 | Orlistat is an approved reversible general lipase inhibitor with IC50 of 122 ng/mL, used to treat obesity. |
| FB11222 | LCL521 | 1226851-11-1 | LCL521, an inhibitor of acid ceramidase, shows anticancer actions of lysosomally targeted. |
| FB11223 | LCL521 2HCl | 1226759-47-2 | LCL521 2HCl, an inhibitor of acid ceramidase, shows anticancer actions of lysosomally targeted. |
| FB02817 | KML29 | 1380424-42-9 | KML29 is a highly selective and potent MAGL inhibitor with IC50s for 15, 43, and 5.9 nM in mouse, rat, and human brain proteomes, respectively. |
| FB12216 | JZP 361 | 1680193-80-9 | JZP 361 is a potent and selective reversible MAGL inhibitor with IC50 of 46 nM. |
| FB02505 | JZL 184 | 1101854-58-3 | JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively. |
| FB09446 | JW 642 | 1416133-89-5 | JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively. |
| FB12239 | JJKK 048 | 1515855-97-6 | JJKK 048 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 0.4 nM. |
| FB16492 | Ibrolipim | 133208-93-2 | Ibrolipim is a Lipoprotein lipase activator. |
| FB07251 | Cetilistat | 282526-98-1 | Cetilistat is a novel pancreatic lipase used to treat obesity. |
| FB08691 | Atglistatin | 1469924-27-3 | Atglistatin is a potent, selective and competitive ATGL with IC50 value of 0.7 μM. |
| FB13031 | ABX-1431 | 1446817-84-0 | ABX-1431 works as both a cannabinoid receptor agonist and a MAGL inhibitor. |
| FB12474 | NF 1819 | 1881244-28-5 |