MCT
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
FB12554 | α-Cyano-4-hydroxycinnamic acid | 28166-41-8 | α-Cyano-4-hydroxycinnamic acid is a MCT inhibitor with antitumoral and antiangiogenic activity. |
FB12697 | SR 13800 | 227321-12-2 | SR13800 is a cell-permeable inhibitor of monocarboxylate transporter 1 (MCT1). |
FB15288 | BAY8002 | 724440-27-1 | BAY-8002 is a potent MCT Inhibitor with IC50 value of 8nM for inhibition of L-lactate uptake. |
FB09455 | AZD3965 | 1448671-31-5 | AZD3965 is a potent, selective and orally available monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM. |
FB08817 | AR-C155858 | 496791-37-8 | AR-C155858 is an inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2 (Ki values are 2.3 and < 10 nM, respectively), and exhibits no activity at MCT4. |
FB03260 | 7ACC2 | 1472624-85-3 | 7ACC2 is a potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx for antitumor treatment targeting lactate transport in cancer cells. |
FB00234 | 7ACC1 | 50995-74-9 | 7ACC1 selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment and inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters. |