Sesquiterpenoids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB10769 | β-Elemene | 515-13-9 | β-Elemene is a natural sesquiterpene found in various plants and imparts floral aromas to some plants. This compound has been reported to inhibit the proliferation of a wide range of tumors. |
| FB07914 | α-Cyperone | 473-08-5 | α-Cyperone, a natural product isolated and purified from the hizomes of Cyperus rotundus L., is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation. |
| FB06454 | Stachybotramide | 149598-71-0 | Stachybotramide, a natural product isolated and purified from the mycelia and culture broth of Stachybotrys sp. MF347, preferentially stimulates the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to both very low density lipoprotein (VLDL) and low density lipoprotein (LDL). |
| FB06420 | Shizukaol D | 142279-42-3 | Shizukaol D, a natural product isolated and purified from the herbs of Chloranthus japonicus, exerts a growth inhibition effect on liver cancer cells in a dose- and time-dependent manner by modulating wnt signalling pathway, and induces mitochondrial dysfunction by depolarizing the mitochondrial membrane and suppressing energy production, which may result in AMPK activation, suggests that shizukaol D may be used to treat metabolic syndrome. |
| FB05571 | Pterosin B | 34175-96-7 | Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. |
| FB05571 | Pterosin B | 34175-96-7 | Pterosin B is a natural product isolated and purified from the aerial parts of Pteris semipinnata, is a salt-inducible kinase 3 (Sik3) pathway inhibitor, preventing chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. |
| FB10063 | Polyphyllin H | 81917-50-2 | Polyphyllin H is a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch.. |
| FB08632 | Parthenolide | 20554-84-1 | Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium) with multiple biological functions. Parthenolide inhibits the growth of the promastigote form of L. amazonensis with IC50 of 3.6 μg/mL, induces apoptosis in cancer cells and blocks inflammation by inhibiting signaling through NF-κB. |
| FB00080 | Palustrol | 5986-49-2 | Palustrol is a natural product isolated and purified from the herbs of Eucalyptus dives. |
| FB06452 | Mollisorin A | 72704-04-2 | Mollisorin A is a natural product isolated and purified from the aerial parts of Ophryosporus lorentzii. |
| FB03430 | Linderane | 13476-25-0 | Linderane, a natural product isolated and purified from the roots of Lindera aggregata( Sims) Kosterm, is an inactivator of CYP2C9. |
| FB04979 | Isofuranodiene | 57566-47-9 | Isofuranodiene, a natural product isolated and purified from the herbs of Chloranthus spicatus, has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells, protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases and can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents. |
| FB04875 | Isoeugenyl Acetate | 5912-87-8 | Isoeugenyl acetate is a natural product isolated and purified from Cinnamon bark oil. |
| FB06606 | Guajadial B | 1414455-03-0 | Guajadial B, a natural product isolated and purified from the herbs of Psidium guajava, shows cytotoxicities against five human cancer cell lines, and is the most effective having an IC50 value of 150 nM toward A549 cells. Guajadial B also acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. |
| FB07322 | Guaiol | 489-86-1 | Guaiol, a natural product isolated and purified from the roots of Ferula ferulaeoides with insecticidal activity, shows significant inhibition of aphids at a concentration of 70 mg/L and good contact activities against the 4th instar larvae of Mythimna separate and 3rd instar larvae of Plutella xylostella, with LD50 values of 0.07 and 8.9 mg/larva, as well as fumigation activity against the 4th instar larvae of M. |
| FB12825 | Guaiazulene | 489-84-9 | Guaiazulene is a derivative of azulene can be used as skin care products ingredients and volatile dye. |
| FB01068 | Germacrone | 6902-91-6 | Germacrone, a natural product isolated and purified from the rhizoma of Curcuma wenyujin with anti-tumor activity, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway, and may be a potent chemopreventive drug candidate for liver cancer via regulating the expression of proteins related to G2/M cell cycle and apoptosis, and p53 and oxidative damage may play important roles in the inhibition of human hepatoma cells growth by germacrone. |
| FB01618 | Fraxinellone | 28808-62-0 | Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2+ channel, while dictamine relaxed the rat aorta by suppressing the Ca2+ influx through both voltage-dependent and receptor-operated Ca2+ channels, and can dramatically induce apoptosis of activated peripheral CD4(+) T cells in vivo, consequently resulting in less CD4(+) T-cell activation and infiltration to the liver. |
| FB06588 | F1839-I | 159096-49-8 | F1839-I is a natural product isolated and purified from plants. |
| FB09039 | Eupalinolide B | 877822-41-8 | Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC. |
| FB09039 | Eupalinolide B | 877822-41-8 | Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC. |
| FB06607 | Epiguajadial B | 1411629-26-9 | Epiguajadial B is a natural product isolated and purified from the herbs of Psidium guajava. |
| FB12820 | Dihydroactinidiolide | 17092-92-1 | Dihydroactinidiolide is a volatile terpene occurs naturally in plants and animals. It is a component of pheromones in insects and may also shows potent phytotoxin and anticancer activity. |
| FB07059 | Curcumol | 4871-97-0 | Curcumol is a sesquiterpene originally isolated from curcuma rhizomes showing anticancer activities both in vitro and in vivo. |
| FB04451 | Cryptomeridiol | 4666-84-6 | Cryptomeridiol, a natural product isolated and purified from the herbs of Blumea balsamifera DC, exhibits a significant and concentration-dependent inhibitory effect on platelet-activating factor receptor binding, and has low activity against A. |
| FB08196 | Costunolide | 553-21-9 | Costunolide shows anti-inflammatory and anti-oxidant activities and also induces apoptosis. It is a sesquiterpene lactone isolated from stem bark of Magnolia sieboldii, |
| FB10578 | Chloramultilide B | 1000995-47-0 | Chloramultilide B exhibits moderate in vitro antifungal activity. |
| FB06586 | Chartarlactam A | 1528745-88-1 | Chartarlactam A, a natural product isolated and purified from the solid cultures of Stachybotrys chartarum, shows antihyperlipidemic effects in HepG2 cells. |
| FB08127 | Carabrone | 1748-81-8 | Carabrone, a natural product isolated and purified from the herbs of Carpesium abrotanoides, exhibit antifungal activities in vitro or in vivo. |
| FB05260 | Brevilin A | 16503-32-5 | Brevilin A, a natural product isolated and purified from the herbs of Centipeda minima, is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STATs, and has antigiardial activity (IC50 = 16.1 μM) and was similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). |
| FB09479 | Blumenol C Glucoside | 135820-80-3 | Blumenol C glucoside is a natural product isolated and purified from the barks of Pseudolarix amabilis. |
| FB10430 | Bilobalide | 33570-04-6 | Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba. |
| FB06459 | Bakkenolide IIIa | 915289-60-0 | Bakkenolide-IIIa, a natural product isolated and purified from the rhizomes of Petasites formosanusi with antioxidant and europrotective effects, protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB signaling. |
| FB02687 | Atractyloside A | 126054-77-1 | Atractyloside A is a natural TCM reference compound. |
| FB01519 | Atractylenolide III | 73030-71-4 | Atractylenolide III, a natural product isolated and purified from the rhizome of Atractylodes macrocephala Koidz., may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury, and is a potential candidate for treatment of human lung carcinoma by inducing the release of cytochrome c, upregulating the expression of bax and translocating apoptosis-inducing factor. |
| FB01520 | Atractylenolide I | 73069-13-3 | Atractylenolide I, a natural compound extracted from largehead atractylodes rhizome, induces apoptosis and brings about cytotoxicity of human promyeloleukemic HL-60 cells. It is also a TLR4-antagonizing agent. |
| FB06832 | Arglabin | 84692-91-1 | Arglabin is a sesquiterpene gamma-lactone is isolated from Artemisia glabella and an anticancer natural compound. |
| FB06888 | Alismoxide | 87701-68-6 | Alismoxide is a natural product isolated and purified from Curcuma comosa. |
| FB08090 | Alantolactone | 546-43-0 | Alantolactone is a sesquiterpene lactone with potential activity against triple-negative breast cancer MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3) signaling pathway. |
| FB05838 | 9-Oxo-10,11-Dehydroageraphorone | 79491-71-7 | 9-Oxo-10,11-dehydroageraphorone, a natural product isolated and purified from the herbs of Eupatorium adenophorum with acaricidal activity, induces hepatotoxicity and cholestasis in rats, effectively inhibits the proliferation of HeLa cells by arresting the cell cycle transition from S to G2/M phase, did not continue to complete the cell cycle activity and induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells. |
| FB06582 | 6-O-Acetylcoriatin | 1432063-63-2 | 6-O-Acetylcoriatin is a natural product isolated and purified from plants. |
| FB06457 | 6-Epi-Albrassitriol | 178456-58-1 | 6-epi-Albrassitriol is a natural product isolated and purified from plants. |
| FB06587 | 4E-Deacetylchromolaenide 4'-O-Acetate | 104736-09-6 | 4E-Deacetylchromolaenide 4'O-acetate is a natural product isolated and purified from plants. |
| FB06453 | 3-Epichromolaenide | 89913-53-1 | 3-Epichromolaenide is a natural product isolated and purified from plants. |
| FB06455 | 2α-Hydroxyeupatolide 8-O-Angelate | 72229-39-1 | 2α-Hydroxyeupatolide 8-O-angelate is a natural product isolated and purified from the herbs of Eupatorium chinense var. tozanense. |
| FB06456 | 2α-Hydroxy-8β-(2-Methylbutyryloxy)costunolide | 128286-87-3 | 2α-Hydroxy-8β-(2-methylbutyryloxy)costunolide is a natural product isolated and purified from plants. |
| FB06584 | 10-O-Acetylisocalamendiol | 1432064-69-1 | 10-O-Acetylisocalamendiol is a natural product isolated and purified from plants. |
| FB09622 | (RS)-Abscisic Acid | 14375-45-2 | (RS)-abscisic acid is a natural product act as a negative regulator of plant growth. |
| FB07321 | (-)-Globulol | 489-41-8 | (-)-Globulol is a natural product isolated and purified from the fruits of Eucalyptus globulus Labill., showing antimicrobial activity against Xanthomonas vesicatoria and Bacillus subtilis, the IC50 value of 158.0 mg/ mLand 737.2 mg/ mL, respectively. |
| FB00820 | Nardosinone | 23720-80-1 |