Phenols
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB08156 | Urolithin A | 1143-70-0 | Urolithin A is a metabolite of ellagitannin with antiproliferative and antioxidant properties. It can cross the blood brain barrier, and may have neuroprotective effects against Alzheimer’s Disease. |
| FB02471 | Thymol | 89-83-8 | Thymol, a natural product isolated and purified from the herbs of Thymus serpyllum L., is a positive allosteric modulator of human GABAA receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster. |
| FB04214 | Rottlerin | 82-08-6 | Rottlerin, a principal phenolic compound isolated and purified from Kamala plant Mallotus philippinensis, exers its tumour-suppressive function in ACC. |
| FB09009 | Rhaponticin | 155-58-8 | Rhapontin is a natural product isolated and purified from the roots of Rhei Rhizoma. |
| FB02125 | Rhapontigenin | 500-65-2 | Rhapontigenin, a natural product isolated and purified from the rhizomes of Rheum undulatum with antioxidative, antihyperlipidemic, and antifungal activities, inhibits tyrosinase activity and melanin synthesis in B16F10 melanoma cells and HIF-1α accumulation and angiogenesis in PC-3 prostate cancer cells, suppresses breast cancer cell migration and invasion, which is involved in inhibiting the PI3K-dependent Rac1 signaling pathway. |
| FB08891 | Punicalagin | 65995-63-3 | Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T. |
| FB13004 | Phloretic acid | 501-97-3 | Phloretic Acid can defense influenza through augmentation of type I interferon signaling, it's a microbially associated metabolite and a naturally occurring phenolic compound. |
| FB05234 | Moracin P | 102841-46-3 | Moracin P, a natural product isolated and purified from the root bark of Morus alba L., shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells, exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia, and might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells. |
| FB08585 | Methyl Orsellinate | 3187-58-4 | Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM. |
| FB08585 | Methyl Orsellinate | 3187-58-4 | Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM. |
| FB02917 | Kakoul | 18607-90-4 | Kakuol, a natural product isolated and purified from the roots of Asarum sieboldii Miq. with antifungal activity, can completely inhibit the mycelial growth of Botrytis cinerea Pers ex Fr and Cladosporium cucumerinum Ellis & Arthur at 50 microg ml (-1) and 30 microg ml (-1), respectively, and is able to inhibit the DNA relaxation mediated by the human enzyme. |
| FB07249 | Isovanicaline | 621-59-0 | Isovanicaline, a natural product isolated and purified from the barks of Pinus yunnanensis, is a selective inhibitor of aldehyde oxidase, is metabolized by aldehyde dehydrogenase into isovanillic acid ,and the LD50 (rat, ipr) is 1276 mg/kg. |
| FB11606 | Hispidin | 555-55-5 | Hispidin is a polyphenol originally isolated from P. hispidus that has diverse biological activities, including antioxidant, anti-inflammatory, and cytoprotective properties. |
| FB04757 | Hirsutenone | 41137-87-5 | Hirsutenone, a natural product isolated and purified from the eaves of Alnus nepalensis, exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2, attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity, and may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. Hirsutenone showed potent PL(pro) inhibitory activity with IC50 value of 4.1µM. |
| FB02098 | Hinokitiol | 499-44-5 | Hinokitiol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. It can partially mimic the function of missing protein transporters of iron, and possibly other ions, may have potential in treating human diseases. |
| FB00315 | Higenamine | 5843-65-2 | Higenamine is a natural product isolated and purified from the aconite root |
| FB04350 | Goniothalamin | 17303-67-2 | Goniothalamin, a natural product isolated and purified from the herbs of Goniothalamus griffithii, enhances rather than inhibits the ATPase activity of a cyanobacterial Hsp90 (HtpG) and a yeast Hsp90, increases both K(m) and k(cat) of the Hsp90s. |
| FB02092 | Ginkgolic Acid | 22910-60-7 | Ginkgolic acid is a natural product isolated and purified from the leaves of Ginkgo biloba L.with suspected cytotoxic, allergenic, mutagenic and carcinogenic properties. |
| FB01156 | Gentisic Acid | 490-79-9 | Gentisic acid is a natural product isolated and purified from the roots of Gentiana scabra Bunge. |
| FB12860 | Ethyl Vanillate | 617-05-0 | Ethyl Vanillate is a flavouring agent exhibits strong antioxidant activity, it's a vanillin analog, also used in the food industry. |
| FB08939 | Ethyl 2,4,6-Trihydroxybenzoate | 90536-74-6 | Ethyl 2,4,6-trihydroxybenzoate, a natural product isolated and purified from the herbs of Celtis biondii, suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes, and is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells. |
| FB05541 | Dihydropinosylvin | 14531-52-3 | Dihydropinosylvin, is a natural product isolated and purified from the herbs of Dioscorea rotundata with anti-fungal activity. |
| FB10434 | Desoxyrhaponticin | 30197-14-9 | Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
| FB10434 | Desoxyrhaponticin | 30197-14-9 | Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
| FB01992 | DehydropachyMic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
| FB01992 | DehydropachyMic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
| FB01992 | DehydropachyMic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
| FB01992 | DehydropachyMic acid | 77012-31-8 | Dehydropachymic acid is extracted from the root of wolfiporia cocos (Schw.) Ryv. with antiinflammatory activity. |
| FB05826 | Cryptofolione | 160098-78-2 | Cryptofolione, a natural product isolated and purified from the fruits of Cryptocarya alba, acts as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitor can force cells arrested in G(2) phase by DNA damage to enter mitosis, and shows moderate cytotoxicity in both macrophages and T. |
| FB05231 | Cristacarpin | 74515-47-2 | Cristacarpin, a natural product isolated and purified from the herbs of Erythrina burana, exhibits moderate but selective activity towards DNA repair-deficient yeast mutants, and promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxygen species (ROS) generation and which eventually terminates by triggering senescence in pancreatic and breast cancer cells through blocking the cell cycle in the G1 phase. |
| FB11287 | Cannabidivarin | 24274-48-4 | Cannabidivarin is a non-psychoactive cannabinoid found in Cannabis that activates CB2 cannabinoid receptors as well as the transient receptor potential channels TRPA1, TRPV1, and TRPV2 (EC50s = 0.42, 3.6, and 7.3 µM, respectively). It is also reported to antagonize TRPM8 (IC50 = 0.9 µM) and to inhibit diacylglycerol lipase (IC50 = 16.6 µM). |
| FB11341 | Artepillin C | 72944-19-5 | Artepillin C is a major, biologically active ingredient of Brazilian propolis, possesses anticancer activity against several cancer cells with different tissue origins. |
| FB04742 | alpha-Viniferin | 62218-13-7 | alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages. |
| FB07551 | Alnustone | 33457-62-4 | Alnustone is a natural product isolated and purified from the seeds of Alpinia katsumadai Hayata exerting significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats. |
| FB02969 | Agrimol B | 55576-66-4 | Agrimol B is a natural product isolated and purified from the herbs of Agrimonia pilosa Ledeb. |
| FB12801 | Acetosyringone | 2478-38-8 | Acetosyringone is a phenolic natural product secreted by wounded plant tissues, is widely used to increase efficacy of genetic transformation for the creation of genetically modified dicotyledonous and monocotyledonous plants. |
| FB07050 | 8-Gingerol | 23513-08-8 | 8-Gingerol, a natural product isolated and purified from the rhizome of Zingiber officinale Roscoe. |
| FB00620 | 4-Hydroxybenzoic Acid | 99-96-7 | 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties. |
| FB12856 | 4-Ethylphenol | 123-07-9 | 4-Ethylphenol is also known as 4-EP which is a para-substituted phenolic compound found in red wine. |
| FB05235 | 3-Hydroxybakuchiol | 178765-54-3 | 3-Hydroxybakuchiol, a natural product isolated and purified from the herbs of Psoralea corylifolia Linn., has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells, and exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation. |
| FB04442 | 3,8-Di-O-Methylellagic Acid | 2239-88-5 | 3,8-Di-O-methylellagic acid, a natural product isolated and purified from the peels of Punica granatum L. |
| FB05745 | 3,4-Dihydroxybenzaldehyde | 139-85-5 | 3,4-dihydroxybenzaldehyde, a natural product isolated and purified from the heartwood of Cassia garrettiana, can scavenge DPPH radical, hydroxyl radical and intracellular ROS. |
| FB09969 | 2-Ethyl-5-methylphenol | 1687-61-2 | 2-Ethyl-5-methylphenol is a constituent of Angelica species, it is a metabolite of Penicillium species on barley. |
| FB12978 | 2',5'-Dihydroxyacetophenone | 490-78-8 | 2',5'-Dihydroxyacetophenone is a mixture of various isomers of adihydroxyacetophenone which is used as a flavoring agent. |
| FB04773 | 11-O-Galloylbergenin | 82958-44-9 | 11-O-Galloylbergenin, a natural product isolated and purified from the aerial parts of Bergenia ligulata., shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg. |
| FB00412 | 10-Gingerol | 23513-15-7 | 10-Gingerol, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe. |
| FB05504 | (-)-Variabilin | 370102-93-5 | (-)-Variabilin, a natural product isolated and purified from the roots of Angelica sinensis, is an inhibitor of human platelet aggregation. |
| FB05504 | (-)-Variabilin | 370102-93-5 | (-)-Variabilin, a natural product isolated and purified from the roots of Angelica sinensis, is an inhibitor of human platelet aggregation. |
| FB00021 | Curculigoside | 85643-19-2 | |
| FB00021 | Curculigoside | 85643-19-2 |