Adenosine Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB04404 | Xanthine | 69-89-6 | Xanthine is a natural occuring purine-base adenosine receptor antagonist, from which a number of stimulants such as caffeine and theobromine are derived. |
| FB05121 | Vipadenant | 442908-10-3 | Vipadenant is an adenosine antagonist with Ki of 1.3 nM and 68 nM for A2A and A1, respectively. Vipadenant is a selective A2A receptor antagonist with Ki values of 1.3, 68, 63, and 1,005 nM for A2A, A1, A2B, and A3 receptors, respectively, used in development for for Parkinson's disease. |
| FB00095 | Trabodenoson | 871108-05-3 | Trabodenoson is a potent and highly selective adenosine A1 receptor agonist. |
| FB08638 | Theophylline | 58-55-9 | Theophylline is a natural product present in tea and cocoa, working as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. |
| FB11653 | Tecadenoson | 204512-90-3 | Tecadenoson is a selective A1 adenosine receptor agonist. |
| FB17868 | Taminadenant | 1337962-47-6 | Taminadenant is an antagonist of adenosine receptor. |
| FB12400 | SCH 442416 | 316173-57-6 | SCH-442416 is a selective adenosine A2A receptor antagonist. SCH-442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). It displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM). |
| FB12606 | PSB 603 | 1092351-10-4 | PSB 603 is a adenosine A2B receptor antagonist with Ki of 0.553 nM. |
| FB12608 | PSB 36 | 524944-72-7 | PSB 36 is a potent and selective A1 adenosine receptor antagonist that displays binding affinity of 0.12 nM for rA1. |
| FB12607 | PSB 0788 | 1027513-54-7 | PSB 0788 is a potent and selective adenosine A2B receptor antagonist with IC50 of 3.64 nM at human A2B receptor. |
| FB08554 | Proxyphylline | 603-00-9 | Proxyphylline is a xanthine-derivatived antagonists of A1 and A2 adenosine receptors, which relaxe smooth muscles, particularly bronchial muscles. |
| FB12614 | PQ 69 | 910045-32-8 | PQ 69 is a potent and selective A1 receptor inverse agonist taht exhibits high binding affinity at A1 receptor with Kis of 0.07 and 0.96 nM for rat and human receptors respectively. |
| FB12649 | SDZ WAG 994 | 130714-47-5 | Potent, selective A1 agonist |
| FB12706 | TC-G 1004 | 1061747-72-5 | Potent and selective A2A antagonist |
| FB10736 | Norisoboldine | 23599-69-1 | Norisoboldine is an isoquinoline alkaloid isolated and purfied from the roots of Lindera aggregata, which acts as an AhR agonist, and enhances the function of the adenosine A1 receptor. |
| FB10887 | Neladenoson Dalanate | 1239309-58-0 | Neladenoson dalanate is a potent and selective adenosine A1 receptor agonist, and potentially useful for treatment of cardiovascular diseases. |
| FB06911 | N6-[2-(4-Aminophenyl)ethyl]adenosine | 89705-21-5 | N6-[2-(4-Aminophenyl)ethyl]adenosine is a potent, non-selective A3 adenosine receptor agonist. |
| FB12403 | N6-Cyclopentyladenosine | 41552-82-3 | N6-Cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist with Ki of 2.3 nM for human A1 receptor. |
| FB07159 | N-[(4-Aminophenyl)methyl]adenosine | 95523-13-0 | N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor, with Ki of 29 nM for rat ecto-5′-nucleotidase. |
| FB16698 | N-(2-Hydroxyethyl)adenosine | 4338-48-1 | N-(2-Hydroxyethyl)adenosine has been studied as an anticonvulsant through the activation of adenosine A1 receptor (AA1R). It attenuates cell death induced by H2O2 through antioxidant action. |
| FB12465 | MRS 5698 | 1377273-00-1 | MRS 5698 is a high affinity and selective A3 adenosine receptor agonist with Ki ~ 3 nM. |
| FB12480 | MRS 3777 Hemioxalate | 1186195-57-2 | MRS 3777 Hemioxalate is a high affinity adenosine A3 receptor antagonist with Ki of 47 nM. |
| FB12419 | MRS 1754 | 264622-58-4 | MRS 1754 is a selective adenosine A2B receptor antagonist with Ki of 1.97 nM for hA2B. |
| FB12475 | MRS 1706 | 264622-53-9 | MRS 1706 is a potent and selective adenosine A2B receptor inverse agonist with Ki of 1.39 nM. |
| FB06899 | LUF6000 | 890087-21-5 | LUF6000 is an allosteric modulator of the human A3 adenosine receptor (AR). |
| FB02487 | LAS38096 | 851371-22-7 | LAS38096 is a potent, selective, and efficacious A2B adenosine receptor antagonist. |
| FB12295 | KW 3902 | 136199-02-5 | KW 3902 is a Selective adenosine A1 receptor antagonist with Ki of 0.19 nM. |
| FB12518 | ISAM 140 | 932191-62-3 | ISAM 140 is a high affinity A2B receptor antagonist with Ki of 3.49 nM. |
| FB12653 | SCH 202676 Hydrobromide | 265980-25-4 | Inhibitor of ligand binding to G-protein-coupled receptors |
| FB01571 | IB-MECA | 152918-18-8 | IB-MECA is an agonist of the adenosine A3 receptor with EC50 values of 0.11 μM. IB-MECA is a potent and selective A3 adenosine receptor agonist with Ki value of 1.1, 54 and 56 nM for A3, A1 and A2A receptors, respectively, which possessing cardioprotective effect and reduces infarct size upon reperfusion in rats. |
| FB12269 | HEMADO | 403842-38-6 | HEMADO is a high affinity and selective adenosine A3 receptor agonist with Ki of 1.1 nM for human A3. |
| FB02410 | GR79236 | 124555-18-6 | GR79236 is a highly potent and selective adenosine A1 receptor agonist (Ki = 3.1 nM) that has analgesic and anti-inflammatory actions in humans and animals. |
| FB12515 | DPCPX | 102146-07-6 | DPCPX is a potent and selective A1 adenosine receptor antagonist, both in vitro and in vivo, with Ki of 3.9 nM for human A1. |
| FB12650 | SLV 320 | 251945-92-3 | Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats[1]. |
| FB12534 | CVT-6883 | 752222-83-6 | CVT-6883 is a selective antagonist of adenosine A2B receptors with Ki of 22 nM for human A2B. |
| FB11597 | CPI444 | 1202402-40-1 | CPI-444 is an orally administered antagonist of the adenosine A2A receptor. Upon oral administration, CPI-444 binds to adenosine A2A receptors expressed on the surface of immune cells, including T-lymphocytes, natural killer (NK) cells, macrophages and dendritic cells (DCs). |
| FB02911 | CGS 21680 HCl | 124431-80-7 | CGS 21680 HCl is A2A adenosine receptor agonist with Ki value of 27 nM, which can be used to distinguish A2A- and A2B-mediated effect and shows affinity for both A1 and A3 adenosine receptors. |
| FB15400 | BAY-545 | 1699717-32-2 | BAY-545 is a structure-optimizd adenosine receptor A2B antagonist with IC50 value of of 59 nM. |
| FB15658 | BAY-218 | 2162982-11-6 | BAY-218 is an AHR antagonist. |
| FB12245 | BAY 60-6583 | 910487-58-0 | BAY 60-6583 is a potent adenosine A2B receptor agonist with EC50 of 2.83 nM for murine A2B receptor. |
| FB17742 | BAY 2416964 | 2242464-44-2 | BAY 2416964 is an antagonist of aryl hydrocarbon receptor (AhR) with IC50 of 341 nM. |
| FB11598 | AZD4635 | 1321514-06-0 | AZD4635 is an A2AR antagonist which can reverse adenosine mediated T cell suppression. |
| FB07494 | Alloxazine | 490-59-5 | Alloxazine is a selective antagonist of A2B adenosine receptor. |
| FB12923 | Adenosine | 58-61-7 | Adenosine is a nucleoside that is composed of adenine and d-ribose and plays many important biological roles in addition to being components of DNA and RNA. |
| FB11714 | Adenosine Antagonist-1 | 431040-19-6 | Adenosine antagonist-1 is an adenosine A3 receptor (AA3R) antagonist. |
| FB16448 | Adenosine amine congener | 96760-69-9 | Adenosine amine congener hydrate is a potent aqueous-soluble A1 adenosine receptor agonist with Ki value of 0.85nM for binding against [3H]N6-cyclohexyladenosine in rat cerebral cortex membranes. |
| FB03280 | AB-MECA | 152918-26-8 | AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors. |
| FB04140 | 2-Cl-IB-MECA | 163042-96-4 | 2-Cl-IB-MECA is a highly selective A3 adenosine receptor agonist with Ki value of 0.33nM, displaying 2500- and 1400-fold selectivity over A1 and A2A receptors, respectively. |
| FB12527 | 2-Chloro-N6-cyclopentyladenosine | 37739-05-2 | 2-Chloro-N6-cyclopentyladenosine is a potent and selective adenosine A1 receptor agonist with Ki of 0.8 nM for human A1. |
| FB12596 | (±)-5'-Chloro-5'-deoxy-ENBA | 103626-26-2 | (±)-5'-Chloro-5'-deoxy-ENBA is a highly selective adenosine A1 receptor agonist with Ki of 0.51 nM. |