3-PGDH

货号 产品名 CAS号 信息
FB17271 PKUMDL-WQ-2101 304481-72-9 PKUMDL-WQ-2101 is a negative allosteric modulator of PHGDH (phosphoglycerate dehydrogenase) with IC50 value of 34.8μM.
FB11928 NCT-503 1916571-90-8 NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 µM.1 It has been shown to reduce the production of glucose-derived serine in cells and to suppress the growth of PHGDH-dependent MDA-MB-468 cancer cells both in vitro and in mice bearing orthotopic xenograft tumors
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