货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
FB17271 | PKUMDL-WQ-2101 | 304481-72-9 | PKUMDL-WQ-2101 is a negative allosteric modulator of PHGDH (phosphoglycerate dehydrogenase) with IC50 value of 34.8μM. |
FB11928 | NCT-503 | 1916571-90-8 | NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 µM.1 It has been shown to reduce the production of glucose-derived serine in cells and to suppress the growth of PHGDH-dependent MDA-MB-468 cancer cells both in vitro and in mice bearing orthotopic xenograft tumors |