| FB08965 |
R121919
|
195055-03-9 |
R121919 is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types. |
| FB15759 |
Pexacerfont
|
459856-18-9 |
Pexacerfont is a potent and selective antagonist with IC50 value of 6.1nM. |
| FB11683 |
GSK561679
|
885220-61-1 |
GSK561679 is a CRF-1 antagonist. Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a potential treatment for alcoholism. |
| FB11788 |
Emicerfont
|
786701-13-1 |
Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM. |
| FB00012 |
Corticotropin-releasing Factor Ovine
|
79804-71-0 |
Corticotropin-releasing factor (ovine) , a preferential CRF1 receptor agonist, shows almost 200-fold greater affinity for the CRF1 than CRF2 receptor. |
| FB00010 |
CRF (human, rat)
|
86784-80-7 |
Corticotropin-releasing factor (human) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary. |