Lignans
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB04723 | Yangambin | 13060-14-5 | Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role. |
| FB04723 | Yangambin | 13060-14-5 | Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role. |
| FB05202 | Wallichinine | 125292-97-9 | Wallichinine, a natural product isolated and purified from the stems of Piper wightii, shows inhibitory activity on platelet aggregation caused by platelet activating factor (PAF), significantly potentiates the effects of two ABCB1 substrates vincristine and doxorubicin on inhibition of growth, arrest of cell cycle and induction of apoptosis in ABCB1 overexpressing cancer cells, and the overexpression of ABCB1 in cancer cells is one of the main reasons of cancer multidrug resistance (MDR), suggesting that wallichinine with ABCB1 presents valuable clues for the development of MDR reversal reagents from natural products. |
| FB06575 | Vitexdoin A | 1186021-77-1 | Vitexdoin A is a natural product isolated and purified from the herbs of Vitex negundo. |
| FB03573 | Tracheloside | 33464-71-0 | Tracheloside, a natural product isolated and purified from the herbs of Trachelospermum jasminoides (Lindl.) Lem., significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC50 value of 0.31 mg/mL, a level of inhibition comparable to that of tamoxifen (IC50 = 0.43 mg/mL). |
| FB06377 | threo-7-O-Methylguaiacylglycerol β-Coniferyl Ether | 150333-85-0 | threo-7-O-Methylguaiacylglycerol β-coniferyl ether is a natural product isolated and purified from plants. |
| FB04795 | Sesamin | 607-80-7 | Sesamin is a natural product derived from sesame seeds, acting as a potent serum lipid-lowering food component. |
| FB05207 | Schizandriside | 71222-06-5 | Schizandriside, a natural product isolated and purified from the leaves of Miconia rubiginosa with anti-inflammatory effect, shows significant cytotoxicity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines with inhibitory concentration (IC50) values of 3.26-8.89 uM, and has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells. |
| FB10619 | Schizandrin | 7432-28-2 | Schizandrin is a natural product possessing antioxidant and anti-inflammatory activities. |
| FB06229 | Schisantherin E | 64917-83-5 | Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd. |
| FB09835 | Schizantherin B | 58546-55-7 | Schisantherin B is a natural product isolated and purified from the seeds of Schisandra chinensis (Turcz.) Baill. showing good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. |
| FB04792 | Schisantherin A | 58546-56-8 | Schisantherin A is a natural product isolated and purified from the herbs of Chelidonium majus with anti-microbial, anti-oxidant and anti-inflammatory properties, and is a specific inhibitor of Rac1b. |
| FB09351 | Schisandrin B | 61281-37-6 | Schisandrin B is a naturally occuring anti-inflammatory and antioxidant agent which can inhibit ROS production in microglia. |
| FB09352 | Schisandrin A | 61281-38-7 | Schisandrin A is a naturally occuring agonist of the adiponectin receptor 2 with an IC50 value of 3.5 µM. |
| FB04696 | Savinin | 493-95-8 | Savinin, a natural product isolated and purified from the heartwood of Pterocarpus santalinus with antiinflammatory effect, can significantly inhibit tumor necrosis factor (TNF)-a production in lipopolysaccharide (LPS)-stimulated RAW264.7 cells, and T cell proliferation elicited by concanavalin (Con A), without displaying cytotoxicity, and also exhibits potent spermicidal activity and significant insecticidal activity. |
| FB01517 | Pinoresinol | 487-36-5 | Pinoresinol, a natural product isolated and purified from the bark of Eucommia ulmoides Oliver, may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C. |
| FB06227 | Pinoresinol Diglucoside | 63902-38-5 | Pinoresinol diglucoside is one of the major lignans with various pharmacological activities which could be isolated from Duzhong and other plant species. |
| FB06499 | Phillyrin | 487-41-2 | Phillyrin is a naturally occuring AMPK activity enhancer, isolated and purified from the fruits of Forsythia suspensa. |
| FB04695 | Paulownin | 13040-46-5 | Paulownin, a natural product isolated and purified from the barks of Paulownia tomentosa, is active against the MCF-7 breast cancer cell line with IC50 values of 14.0 uM, and has the action of anti-inflammation, analgesia, immunity, hypoglycemia and has little toxicity. |
| FB06576 | Nyasicol 1,2-Acetonide | 1432057-64-1 | Nyasicol 1,2-acetonide is a natural product isolated and purified from plants. |
| FB10559 | Nortrachelogenin | 34444-37-6 | Nortrachelogenin, a natural product isolated and purified from the herbs of Trachelospermum jasminoides, shows effects on the central nervous system producing depression in rabbits and is an agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors (GFRs), thereby efficiently synergizing with TRAIL exposure. |
| FB04688 | Niranthin | 50656-77-4 | Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites. |
| FB04688 | Niranthin | 50656-77-4 | Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites. |
| FB02963 | Licarin B | 51020-87-2 | Licarin B is a naturally occuring neolignan isolated from seeds of Myristica fragrans. |
| FB04702 | Isotaxiresinol | 26194-57-0 | Isotaxiresinol, a natural product isolated and purified from the branch of Taxus wallichiana, may be useful for treatment of postmenopausal osteoporosis, especially for prevention of bone fracture induced by estrogen deficiency, and prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha. |
| FB04708 | Futoquinol | 28178-92-9 | Futoquinol, a natural product isolated and purified from the herbs of Piper kadsura with anti-neuroinflammatory activity, can potently inhibit NO production with an IC(50) value of 16.8 mM in microglia cells, and shows potent inhibition of PMA-induced ROS production in human polymorphonuclear neutrophils with IC(50) values 13.1 +/- 5.3 mM. |
| FB06378 | Futokadsurin C | 852459-91-7 | Futokadsurin C, a natural product isolated and purified from the aerial parts of Piper futokadsura, can inhibit nitric oxide production by a murine macrophage-like cell line (RAW 264.7), which is activated by lipopolysaccharide and interferon-gamma. |
| FB04710 | Eudesmin | 526-06-7 | Eudesmin, a natural product isolated and purified from the dry leaves of Haplophyllum perforatum Kar.et Kir. |
| FB06375 | erythro-Guaiacylglycerol-β-O-4'dehydrodisinapyl Ether | 613684-55-2 | erythro-Guaiacylglycerol-β-O-4'dehydrodisinapyl ether is a natural product isolated and purified from the seed shell of Hevea brasiliensis, showing inhibitory activity against human leukocyte elastase with the IC50 value of 171 umol·L-1. |
| FB06381 | erythro-Guaiacylglycerol β-Sinapyl Ether 7-O-Glucoside | 412029-03-9 | erythro-Guaiacylglycerol β-sinapyl ether 7-O-glucoside is a natural product isolated and purified from plants. |
| FB06376 | erythro-Guaiacylglycerol β-Dihydroconiferyl Ether | 135820-77-8 | erythro-Guaiacylglycerol β-dihydroconiferyl ether is a natural product isolated and purified from the herbs of Canadian maple syrup. |
| FB01311 | Enterolactone | 78473-71-9 | Enterolactone is a mammalian lignan formed by the action of intestinal bacteria from plant lignan precursors present in the diet and is potential anti-cancer effect. |
| FB01310 | Enterodiol | 80226-00-2 | Enterodiol is a mammalian lignan formed by the action of intestinal bacteria from plant lignan precursors present in the diet and is potential anti-cancer effect. |
| FB06636 | DL-Syringaresinol | 1177-14-6 | DL-Syringaresinol, a natural product isolated and purified from the herbs of Liriodendron tulipifera, shows inhibitory activity of Helicobacter pylori motility with the IC50 value is 50 mg/mL, potently inhibit the proliferation of human promyelocytic HL-60 cells through G1 arrest and induction of apoptosis, induces vasorelaxation by enhancing NO production in endothelial cells via two distinct mechanisms, phosphatidylinositol 3-kinase/Akt- and (PLC)/Ca2+/CaMKKβ -dependent eNOS phosphorylation and Ca(2+)-dependent eNOS dimerization, and protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism. |
| FB04432 | Dihydroguaiaretic Acid | 66322-34-7 | Dihydroguaiaretic acid, a natural product isolated and purified from the aerial parts of Saururus chinensis. |
| FB05197 | Denudatin B | 87402-88-8 | Denudatin B, a natural product isolated and purified from the herbs of Kadsura coccinea, inhibits the aggregation and ATP release of washed rabbit platelets caused by platelet-activating factor (PAF) in a concentration-dependent manner, has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin, relaxes vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels and its effect to increase cGMP may enhance the vasorelaxation and shows potent 2, 2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging activity. |
| FB06374 | Demethylcarolignan E | 873694-46-3 | Demethylcarolignan E is a natural product isolated and purified from the stems of Hibiscus taiwanensis. |
| FB02945 | Dehydrodiisoeugenol | 2680-81-1 | Dehydrodiisoeugenol, a natural product isolated and purified from the seeds of Myristica fragrans Houtt. |
| FB02945 | Dehydrodiisoeugenol | 2680-81-1 | Dehydrodiisoeugenol, a natural product isolated and purified from the seeds of Myristica fragrans Houtt. |
| FB04434 | Dehydrodiconiferyl Alcohol | 4263-87-0 | Dehydrodiconiferyl alcohol, a natural product isolated and purified from the stems of Cucurbita moschata., shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts, and can modulate the differentiation of Th17 and Th1 cells and suppress experimental autoimmune encephalomyelitis, it may be a potential candidate as an agent for the control of Th17 and Th1-mediated inflammatory diseases. |
| FB05200 | Cycloolivil | 3064-05-9 | Cycloolivil, a natural polyphenolic antioxidant isolated and purified from the herbs of Maytenus hookeri Loes. |
| FB05469 | Boehmenan | 57296-22-7 | Boehmenan, a natural product isolated and purified from the herbs of Euphorbia hirta Linn., exhibits cytotoxicity against both Wnt-dependent (HCT116) and Wnt-independent (RKO) cells, and decreases the expression of full, cytosolic and nuclear β-catenin along with c-myc in STF/293 cells, suggesting that boehmenan may have inhibited the Wnt signal by decreasing β-catenin levels. |
| FB10742 | Asarinin | 133-05-1 | Asarinin, a natural product isolated and purified from the herbs of Asarum sieboldii Miq. |
| FB02141 | Arctigenin | 7770-78-7 | Arctigenin is a naturally occuring agonist of adiponectin receptor 1 with IC50 value of 2.6μM. |
| FB07247 | Anwulignan | 107534-93-0 | Anwuligan, a natural product isolated and purified from the fruits of Schisandra chinensis, possesses therapeutic potentials against neurodegenerative diseases with oxidative stress and neuroinflammation. |
| FB06379 | Acetylvirolin | 916264-22-7 | Acetylvirolin is a natural product isolated and purified from plants. |
| FB06373 | 4,4'-Dihydroxy-3,3',9-Trimethoxy-9,9'epoxylignan | 1206464-65-4 | 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'epoxylignan is a natural product isolated and purified from the herbs of Viburnum foetidum, showing cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2 and HCT15). |
| FB13017 | 4'-Demethylpodophyllotoxin | 40505-27-9 | 4'-Demethylpodophyllotoxin shows potent cytotoxic potential in diverse cancer cell lines, it's a lignan isolated from the herb of Dysosma pleiantha (Hance) Woodson. |
| FB06380 | 3,4,5'Trimethoxy-3',4'methylenedioxy-7,9':7',9-Diepoxylignan | 873867-94-8 | 3,4,5'Trimethoxy-3',4'methylenedioxy-7,9':7',9-diepoxylignan is a natural product isolated and purified from plants. |
| FB03532 | (-)-Syringaresnol-4-O-β-D-Apiofuranosyl-(1→2)-β-D-Glucopyranoside | 136997-64-3 | (-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside is a natural product isolated and purified from Albizia julibrissin Duraz.. |