CAS:1098-60-8Triflupromazine hydrochloride

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Triflupromazine HCl 盐酸三氟丙嗪 Cat No. FB00499Cas No. 1098-60-8

Triflupromazine HCl, an antipsychotic, can function as a blocker of dopamine D2 receptor and dopamine D3 receptor in brain. It is used to treat dyskinesia and alcohol withdrawal syndrome.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.5715 mL
- 12.8575 mL
- 25.7150 mL
- 5 mM
- 0.5143 mL
- 2.5715 mL
- 5.1430 mL
- 10 mM
- 0.2572 mL
- 1.2858 mL
- 2.5715 mL
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技术信息

CAS号

1098-60-8

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C18H20ClF3N2S

运输

蓝冰

分子量

388.88

别名

溶解度

DMSO	78.0 mg/mL (200.6 mM)

动物实验配方

靶点数据

生物活性

描述Triflupromazine hydrochloride is an antipsychotic medication, which are Dopamine D1/D2 receptor antagonists^[2]. The antipsychotic phenothiazine triflupromazine exhibited significant antibacterial activity against 279 strains of Gram-positive and Gram-negative bacteria. The minimum inhibitory concentration (MIC) of the drug, according to the agar dilution method, was between 2 and 50 mg/mL for Staphylococcus aureus, and 5 and 100 mg/mL for shigellae and vibrios. Triflupromazine, when injected intraperitoneally into Swiss albino mice at a concentration of 30 mg/mouse (20 g), manifested a significant protection to the mice when they were challenged with 50 median lethal dose (MLD) of Salmonella typhimurium NCTC 74^[3]. At the pH-values of maximum stability, triflupromazine hydrochloride and chlorpromazine hydrochloride are more stable than promazine hydrochloride. On the other hand, the stbility of promazine hydrochloride and triflupromazine hydrochloride in the latter buffer system is slightly higher than that in the former one^[4].