G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17222 | YM-254890 | 568580-02-9 | YM-254890 works as both a selective inhibitor of the Gq protein subfamily and a novel platelet aggregation inhibitor with IC50 value below 0.6μM by blocking the P2Y1 receptor-signal transduction pathway. It isolated from the culture broth of strain QS3666. |
| FB06903 | PH-064 | 892546-37-1 | PH-064 is a sodium channel inhibitor. It is also a selective Gαq inhibitor. It traps Gαq in the empty pocket conformation by permitting GDP exit but interdicting GTP entry. |
| FB03900 | Mastoparan | 72093-21-1 | Mastoparan is a mast cell degranulating peptide originally isolated from vespid wasp venom. It can act as activator of Gi and Go. |
| FB03897 | Mas7 | 145854-59-7 | Mas7, structural analogue of mastoparan isolated from wasp venom, is an activator of G protein via Gαi and Gαo stimulation. |
| FB17223 | FR900359 | 107530-18-7 | FR900359 is a plant-derived depsipeptide which works as a selective inhibitor of Gq/11/14 over all other mammalian Gα isoforms. It suppresses many of the hallmark features that are central to the malignancy of melanoma cells. |