Calcium Channel
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB00939 | Zonisamide | 68291-97-4 | Zonisamide, a 1,2 benzisoxazole derivative, is developed as an antiepileptic drug. |
| FB06246 | Zonisamide Sodium | 68291-98-5 | Zonisamide sodium is a 1,2 benzisoxazole derivative and the first agent of this chemical class to be developed as an antiepileptic drug. |
| FB01036 | Z944 | 1199236-64-0 | Z944 is a T-type calcium channel antagonist potentially for the treatment of pain. Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats. |
| FB16857 | Verapamil | 52-53-9 | Verapamil is a phenylalkylamine class L-type calcium channel blocker. It may be a potential Covid-19 drug. |
| FB00311 | Verapamil HCl | 152-11-4 | Verapamil HCl is a phenylalkylamine class L-type calcium channel blocker. |
| FB17769 | Urolithin C | 165393-06-6 | Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation. |
| FB15356 | TTA-A8 | 1146395-46-1 | TTA-A8 is an antagonist of T-type calcium channels. |
| FB03861 | Tetracaine HCl | 136-47-0 | Tetracaine HCl is a potent local anaesthetic and a channel function allosteric inhibitor. |
| FB12377 | Gadolinium Trichloride | 10138-52-0 | Stretch-activated calcium channel blocker; calcium-sensing receptor agonist |
| FB11729 | SQ-31765 | 138383-07-0 | SQ-31765 is a benzazepine calcium channel blocker. |
| FB10764 | Somatostatin | 51110-01-1 | Somatostatin is an endogenous peptide and inhibits the release of growth hormone, insulin and glucagon by blocking voltage-dependent calcium channels. |
| FB11726 | S107 HCl | 1357476-46-0 | S107 HCl is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. |
| FB12838 | Ruthenium Red | 11103-72-3 | Ruthenium red, a polycationic dye, is an inhibitor of voltage sensitive calcium channel and used in histology to stain aldehyde fixed. |
| FB20250 | Pranidipine | 99522-79-9 | Pranidipine is an effective, long-acting 1,4-dihydropyridine calcium channel blocker. It also has antihypertensive activity. |
| FB08378 | Pinaverium Bromide | 53251-94-8 | Pinaverium bromide acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. |
| FB01161 | Penfluridol | 26864-56-2 | Penfluridol, a T-type calcium channel blocker, is a highly potent, first generation diphenylbutylpiperidine antipsychotic. |
| FB18262 | NS638 | 150493-34-8 | NS-638 is nonpeptide Ca2+-channel blocker with IC50 value of 3.4μM for blocking K+-stimulated intracellular Ca2+-elevation. |
| FB09884 | Norverapamil HCl | 67812-42-4 | Norverapamil HCl is a calcium channel blocker, it is the main active metabolite of verapamil. |
| FB03020 | Nisoldipine | 63675-72-9 | Nisoldipine is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
| FB07562 | Nifedipine | 21829-25-4 | Nifedipine is a dihydropyridine calcium channel blocker, used to lower hypertension and to treat angina. |
| FB07562 | Nifedipine | 21829-25-4 | Nifedipine is a dihydropyridine calcium channel blocker, used to lower hypertension and to treat angina. |
| FB05955 | Neomycin Trisulfate Salt | 1405-10-3 | Neomycin Trisulfate Salt is an aminoglycoside antibiotic and calcium channel protein inhibitor. |
| FB11845 | NecroX-5 | 1383718-29-3 | NecroX-5 is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity. |
| FB11658 | N-type Calcium Channel Blocker-1 | 241499-17-2 | N-type calcium channel blocker-1 is an orally active analgesic agent which shows high affinity to functionally block N-type calcium channels with an IC50 of 0.7 μM in the IMR32 assay |
| FB10329 | MK-8998 | 953778-58-0 | MK-8998 is a potent and selective antagonist of the T-typecalcium channel. |
| FB10330 | Mirogabalin | 1138245-13-2 | Mirogabalin is a preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. |
| FB02507 | Lomerizine 2HCl | 101477-54-7 | Lomerizine 2HCl is an L- and T-type calcium channel blocker used in the treatment of migraine. |
| FB17984 | Levamlodipine | 103129-82-4 | Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina. |
| FB15348 | Lanthanum(III) Chloride Heptahydrate | 10025-84-0 | Lanthanum(III) Chloride Heptahydrate is a calcium channel blocker. |
| FB02098 | Hinokitiol | 499-44-5 | Hinokitiol, an iron chelator originally extracted from woods of Thuja plicata and Chamaecyparis obtuse, has been found to inhibit ultraviolet B-induced apoptosis in keratinocytes of murine ear skin via antioxidant activity of metallothionein. It can partially mimic the function of missing protein transporters of iron, and possibly other ions, may have potential in treating human diseases. |
| FB03164 | GV-58 | 1402821-41-3 | GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 μM for N-type/P-Q-type Ca2+ channel and 20-fold less potent CDK inhibitor activity. |
| FB07216 | Fendiline HCl | 13636-18-5 | Fendiline HCl is a nonselective calcium channel blocker. |
| FB10749 | Felodipine | 72509-76-3 | Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. |
| FB10749 | Felodipine | 72509-76-3 | Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. |
| FB13132 | Ethyl 3-Aminobenzoate methanesulfonate | 886-86-2 | Ethyl 3-Aminobenzoate Methanesulfonate, a hydrophilic derivative of benzocaine, is an anesthetic. |
| FB02264 | Efonidipine HCl | 111011-53-1 | Efonidipine HCl is a dual T-type and L-type calcium channel blocker (CCB). |
| FB07082 | Econazole nitrate salt | 24169-02-6 | Econazole nitrate is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus. |
| FB06749 | DHBP | 6159-05-3 | DHBP is a calcium release inhibitor and a muscle relaxant. |
| FB07605 | Dantrolene Sodium | 14663-23-1 | Dantrolene sodium is an inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. |
| FB12346 | CaCCinh-A01 | 407587-33-1 | CaCCinh-A01 is a dual inhibitor of TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM respectively. |
| FB08188 | Bepridil HCl | 68099-86-5 | Bepridil HCl is a calcium channel blocker, with antianginal activity. |
| FB07172 | (S)-(-)-Bay K 8644 | 98625-26-4 | Bay-K-8644 (S)-(-)- is an agonist of L-type Ca2+ channel. Bay-K-8644 (S)-(-)- activates Ba2+ currents (IBa) (EC50=32 nM). |
| FB07173 | (R)-(+)-Bay K 8644 | 98791-67-4 | Bay-K-8644 (R)-(+)- is a calcium channel inhibitor. Bay-K-8644 (R)-(+)- inhibits Ba2+ currents (IBa) (IC50=975 nM). |
| FB10206 | BAY K 8644 | 71145-03-4 | Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM. |
| FB11617 | Enantiomer of Mirogabalin | 1138245-15-4 | An enantiomer of Mirogabalin. |
| FB00406 | Amlodipine Maleate | 88150-47-4 | Amlodipine Maleate is a long-acting calcium channel blocker. |
| FB00405 | Amlodipine | 88150-42-9 | Amlodipine is a long-acting calcium channel blocker used to lower blood pressure and prevent chest pain. |
| FB15520 | ACT-709478 | 1838651-58-3 | ACT-709478 is a potent, selective, orally-bioavailable and brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively. |
| FB02399 | ABT-639 | 1235560-28-7 | ABT-639 is a peripherally acting, selective T-type Ca2+ channel blocker. |
| FB15245 | A23187 | 52665-69-7 | A23187 is a divalent cation ionophore commonly used to facilitate the movement of Ca2+ into cells, triggering the activation of intracellular calcium-dependent pathways. |