DNA-PK
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
FB17693 | PIK-75 | 372196-67-3 | PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM. |
FB04929 | PIK-75 HCl | 372196-77-5 | PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM. |
FB08821 | NU7441 | 503468-95-9 | NU7441 is a potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM in cell-free assays. |
FB03830 | NU7026 | 154447-35-5 | NU7026 is a potent and selective inhibitor of DNA-PK with IC50 of 0.23 μM. |
FB04598 | NU-7200 | 842122-14-9 | NU-7200 is a potent DNA-PK inhibitor with potential anticancer activity. |
FB01536 | NU-7199 | 69541-04-4 | NU-7199 is a potent DNA-PK inhibitor with potential anticancer activity. |
FB04410 | NU-7031 | 79105-88-7 | NU-7031 is a potent DNA-PK inhibitor with potential anticancer activity. |
FB11540 | M3814 | 1637542-33-6 | M-3814, also known as MSC2490484A and nedisertib, is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities. |
FB12125 | LTURM34 | 1879887-96-3 | LTURM34 shows potent inhibition of DNA-PK (IC50 0.034 μM) with excellent selectivity over the Class I PI3K isoforms (IC50 all > 5 μM) and inhibits the proliferation of a wide range of tumor cell lines. |
FB12562 | DMNB | 20357-25-9 | DMNB is a volatile organic compound used as a detection taggant for explosives. |
FB01666 | Compound 401 | 168425-64-7 | Compound 401 is a DNA-PK synthetic inhibitor with IC50 of 0.28 μM, also targets mTOR. |
FB02385 | CC-115 | 1228013-15-7 | CC-115 is an inhibitor of mTOR and DNA-PK with IC50 of 21 and 13 nM respectively. |
FB02715 | CC-115 HCl | 1300118-55-1 | CC-115 HCl is an inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). |
FB08978 | Brivudine | 69304-47-8 | Brivudine is an antiviral drug acts by inhibiting replication of the target virus, used in the treatment of Herpes Zoster. |
FB11552 | VX-984 | 1562396-65-9 |