IRAK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB00774 | PF-06650833 | 1817626-54-2 | PF-06650833 is an inhibitor ofInterleukin-1 receptor associated kinase 4 (IRAK4), and used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas. |
| FB16536 | IRAK4-IN-4 | 1850276-58-2 | IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor with IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with IC50 of 2.1 nM. |
| FB06166 | IRAK-1-4 Inhibitor I | 509093-47-4 | IRAK-1-4 Inhibitor I is a IRAK-4 inhibitor with IC50 of 200 nM. |
| FB01950 | IRAK Inhibitor 6 | 1042672-97-8 | IRAK Inhibitor 6 is an improved IRAK-4 inhibitor with IC50 value of 160 nM. |
| FB10315 | IRAK Inhibitor 4 trans | 2070014-89-8 | IRAK inhibitor 4 trans is the trans form of IRAK inhibitor 4,which is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. |
| FB01923 | IRAK Inhibitor 4 | 1012104-68-5 | IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. |
| FB01924 | IRAK Inhibitor 3 | 1012343-93-9 | IRAK inhibitor 3 is an interleukin-1 receptor associated kinase inhibitor. |
| FB06960 | IRAK Inhibitor 2 | 928333-30-6 | IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . |
| FB01949 | IRAK Inhibitor 1 | 1042224-63-4 | IRAK inhibitor 1 is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. |
| FB11357 | CA-4948 | 1801343-74-7 | CA-4948 is a selective and potent IRAK4 inhibitor which can be used as a therapeutic agent for hematological cancers with dysregulated TLR/MYD88/IRAK4 signaling. CA-4948 exhibits favorable DMPK properties, oral bioavailability, and is well tolerated in mice. Furthermore, CA-4948 is previously shown to exhibit dose-dependent efficacy in ABC-DLBCL MYD88-L265P xenograft tumor models |
| FB19901 | CA-4948 | 1801344-14-8 | CA-4948 is a selective and orally bioavailable IRAK4 Inhibitor. It exhibited desirable ADME and PK profiles including good oral bioavailability in mice, rat, and dog and showed >90% tumor growth inhibition in relevant tumor models with excellent correlation with in vivo PD modulation. |
| FB12321 | AS 2444697 | 1287665-60-4 | AS 2444697 is a potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with IC50 of 21 nM. |
| FB16157 | Anthraquinone-2-carboxylic Acid | 117-78-2 | Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of fruits and herbs. |