HCV
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB01936 | VX-222 | 1026785-59-0 | VX-222 is a potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. |
| FB10773 | Voxilaprevir | 1535212-07-7 | Voxilaprevir is used for the treatment of Hepatitis C virus infection. |
| FB00537 | Velpatasvir | 1377049-84-7 | Velpatasvir is an inhibitor of hepatitis C virus nonstructural protein 5A (NS5A) (genotype 1 (GT1) to GT6 replicons). |
| FB04794 | VCH-916 | 1200133-34-1 | VCH-916 is a nonnucleoside HCV NS5B polymerase inhibitor. |
| FB06953 | Vaniprevir | 923590-37-8 | Vaniprevir is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease. |
| FB10855 | Uprifosbuvir | 1496551-77-9 | Uprifosbuvir is an uridine nucleotide analog HCV NS5B polymerase inhibitor. |
| FB18013 | Tris(4-aminophenyl)methane | 548-61-8 | Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor. |
| FB09951 | TMC647055 Choline | 1204416-97-6 | TMC647055 choline is a cell-permeating, selective HCV NS5B inhibitor, eliciting a mean IC50 of 34 nM, as assessed in the RdRp primer-dependent transcription assay. |
| FB02191 | Tegobuvir | 1000787-75-6 | Tegobuvir is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor. |
| FB08945 | Simeprevir | 923604-59-5 | Simeprevir is an inhibitor of HCV NS3/4A protease with Ki of 0.36 nM and EC50 of 7.8 nM against viral replication. |
| FB09996 | SB-9200 | 942123-43-5 | SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo. |
| FB10927 | Ruzasvir | 1613081-64-3 | Ruzasvir is a potent, Pan-Genotype HCV NS5A inhibitor with Optimized activity against common resistance-associated polymorphisms. |
| FB02549 | Ribavirin | 36791-04-5 | Ribavirin blocks nucleic acid synthesis and inhibits both RNA and DNA viruses. Ribavirin is a nucleoside antimetabolite antiviral agent. |
| FB05742 | R7128 | 940908-79-2 | R7128 is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes. |
| FB01892 | PSI-7976 | 1190308-01-0 | PSI-7976, the isomer of PSI-7977, is an inhibitor of HCV RNA replication in the HCV replicon assay (EC50=1.07 μM). |
| FB08576 | Procyanidin B1 | 20315-25-7 | Procyanidin B1, a natrual product isolated and prufied from the fruits of Vitis vinifera L., inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with IC50 of 29μM and 15μM, respectively. |
| FB10856 | Pibrentasvir | 1353900-92-1 | Pibrentasvir is a protease inhibitor potentially for the treatment of HCV infection. |
| FB08105 | Paritaprevir | 1216941-48-8 | Paritaprevir is an inhibitor of NS3-4A serine protease that may be used for treatment of hepatitis C. |
| FB08106 | Ombitasvir | 1258226-87-7 | Ombitasvir is inhibitor of hepatitis C virus protein NS5A with EC50s of 0.82 pM to 19.3 pM against HCV genotypes 1 to 5. |
| FB09853 | NM107 | 20724-73-6 | NM107 is an inhibitor of HCV RNA replication with IC50 of 7.0 μM. |
| FB11281 | NIM258 | 1589093-01-5 | NIM258 is a cyclophilin inhibitor with excellent anti-hepatitis C virus potency with decreased transporter inhibition. |
| FB01610 | Nesbuvir | 691852-58-1 | Nesbuvir is a selectively inhibitor of hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase. |
| FB06869 | Narlaprevir | 865466-24-6 | Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor (Ki=6 nM; EC90=40 nM). |
| FB11153 | MK-8876 | 1426960-33-9 | MK-8876 is a HCV NS5B Site D Inhibitor. |
| FB03199 | MK-5172 Sodium | 1425038-27-2 | MK-5172 sodium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
| FB02351 | MK-5172 Potassium | 1206524-86-8 | MK-5172 potassium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
| FB02777 | MK-5172 Hydrate | 1350462-55-3 | MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development. |
| FB16608 | Mecarbinate | 15574-49-9 | Mecarbinate is an anti-hepatitis C virus (HCV) agent. |
| FB03270 | Ledipasvir D-Tartrate | 1502654-87-6 | Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A protein, which is an experimental drug for the treatment of hepatitis C. |
| FB04658 | Ladanein | 10176-71-3 | Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins. |
| FB10019 | KIN1408 | 1903800-11-2 | KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway. |
| FB11772 | JTK-853 | 954389-09-4 | JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0.38 and 0.035 µM in genotype 1a H77 and 1b Con1 strains, respectively. |
| FB02246 | IDX 184 | 1036915-08-8 | IDX 184 is an RNA-directed RNA polymerase (NS5B) inhibitor potentially for the treatment of HCV infection. |
| FB17884 | HCV-IN-30 | 1007882-23-6 | HCV-IN-30 (compound 48) is a HCV NS5A replication complex inhibitor, with IC50s of 901 and 102 nM for genotypes 1a and 1b replicons, respectively. |
| FB17932 | HCV-IN-29 | 1009119-83-8 | HCV-IN-29 is a hepatitis C virus (HCV) inhibitor exacted from patent US8329159B2, compound 1e. |
| FB00356 | GSK2878175 | 1423007-82-2 | GSK2878175 is a pan-genotypic non-nucleoside NS5B polymerase inhibitor potentially for the treatment of HCV infection. |
| FB11177 | GSK-2336805 | 1256390-53-0 | GSK-2336805 is a HCV NS5A inhibitor potentially for the treatment of HCV infection. |
| FB11304 | Glecaprevir | 1365970-03-1 | Glecaprevir is a NS 3/4A inhibitor potentially for the treatment of HCV. |
| FB02805 | Elbasvir | 1370468-36-2 | Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV). It can be used to treat chronic HCV infection. |
| FB06842 | Danoprevir | 850876-88-9 | Danoprevir, a peptidomimetic, is an inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2 nM - 3.5 nM. |
| FB11276 | BMS-986097 | 2131040-32-7 | BMS-986097 is an HCV NS5A inhibitor. |
| FB11246 | BMS-961955 | 1431328-92-5 | BMS-961955 is an allosteric inhibitor of the hepatitis C virus NS5B polymerase. |
| FB10015 | Beclabuvir | 958002-33-0 | Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. |
| FB02476 | Asunaprevir | 630420-16-5 | Asunaprevir is an inhibitor of hepatitis C virus (HCV) NS3 protease. |
| FB10425 | Artemisinin | 63968-64-9 | Artemisinin is an inhibitor of HCV subgenomic replicon. It widely used as anti-malarial drug. |
| FB05120 | Anguizole | 442666-98-0 | Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution. |
| FB11297 | Alisporivir | 254435-95-5 | Alisporivir is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity. |
| FB16606 | AG 1478 hydrochloride | 170449-18-0 | AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV). |
| FB11782 | ACH-806 | 870142-71-5 | ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. |
| FB13014 | 4-Phenoxybenzylamine | 107622-80-0 | 4-Phenoxybenzylamine can stabilize the NS3 protein in an inactive state with IC50 of 500 μM. |