JNK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB09448 | Vacquinol-1 | 5428-80-8 | Vacquinol-1 is an activator of MKK4-dependent macropinocytotic cell death in glioblastoma cells. |
| FB12700 | SR 3576 | 1164153-22-3 | SR-3576 is a potent JNK3 inhibitor that is highly selective over p38. |
| FB02275 | SR-3306 | 1128096-91-2 | SR-3306 is a brain penetrant small molecule JNK inhibitor from the aminopyrimidine class. |
| FB01031 | SP-600125 | 129-56-6 | SP-600125 is a competitive and reversible JNK inhibitor with IC50 values of 40 nM, 40 nM and 90 nM for JNK1, 2 and 3. |
| FB12715 | SU 3327 | 40045-50-9 | Selective JNK inhibitor |
| FB03804 | Kaempferol 3-O-Arabinoside | 5041-67-8 | Kaempferol 3-O-arabinoside is a natural product isolated and purified from the roots of Ligusticum jeholense Nakai et Kitag displaying cytotoxic and high antioxidant activity. |
| FB03804 | Kaempferol 3-O-Arabinoside | 5041-67-8 | Kaempferol 3-O-arabinoside is a natural product isolated and purified from the roots of Ligusticum jeholense Nakai et Kitag displaying cytotoxic and high antioxidant activity. |
| FB04655 | Juglanin | 5041-67-8 | Juglanin, a natural product isolated and purified from the herbs of Phymatopteris hastate with antioxidant activity, shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats, and can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells, it may be a promising candidate for development of anti-tumor drugs targeting breast cancer. |
| FB04655 | Juglanin | 5041-67-8 | Juglanin, a natural product isolated and purified from the herbs of Phymatopteris hastate with antioxidant activity, shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats, and can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells, it may be a promising candidate for development of anti-tumor drugs targeting breast cancer. |
| FB03175 | JNK-IN-8 | 1410880-22-6 | JNK-IN-8 is a potent, selective and irreversible JNK inhibitor with IC50 values of 4.7 nM, 18.7 nM and 1 nM for JNK1, 2 and 3, respectively. |
| FB03173 | JNK-IN-7 | 1408064-71-0 | JNK-IN-7 is a potent inhibitor for JNK all isoforms with IC50 values of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively. |
| FB12729 | TCS JNK 6o | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
| FB12729 | TCS JNK 6o | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
| FB08109 | JNK Inhibitor IX | 312917-14-9 | JNK Inhibitor IX can selectively inhibit JNK2 and JNK3 through targeting the ATP binding site with pIC50 of 6.5 and 6.7, respectively. |
| FB12314 | JIP-1 (153-163) | 438567-88-5 | JIP-1 (153-163) is a peptide inhibitor of c-Jun N-terminal kinase. |
| FB04826 | IQ-1S Free Acid | 23146-22-7 | IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM, with less potency against JNK 1/2 with IC50 values of 390/360nM. |
| FB12261 | IQ 3 | 312538-03-7 | IQ 3 is a selective JNK3 inhibitor with Kd of 66 nM. |
| FB12288 | IQ 1S | 1421610-21-0 | IQ 1S is a JNK inhibitor with Kd of 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively. |
| FB03927 | Ginsenoside Re | 52286-59-6 | Ginsenoside Re is a panaxatriol saponin that has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions. |
| FB00647 | DB07268 | 929007-72-7 | DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. |
| FB12246 | CEP 1347 | 156177-65-0 | CEP 1347 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. |
| FB01042 | CC-930 | 899805-25-5 | CC-930 is a selective ATP-competitive JNK inhibitor with IC50 values of 61nM, 5nM and 5nM for JNK1, 2 and 3, respectively. |
| FB03836 | CC-401 | 395104-30-0 | CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. |
| FB06997 | CC-401 HCl | 1438391-30-0 | CC-401 HCl is a selective and ATP-competitive JNK inhibitor with Ki values ranging in 25-50 nM. |
| FB05134 | BI-78D3 | 883065-90-5 | BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM. |
| FB06836 | AS-602801 | 848344-36-5 | AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively. |
| FB04911 | AS-601245 | 345987-15-7 | AS-601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK) (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM), has neuroprotective properties. |
| FB07769 | Anisomycin | 22862-76-6 | Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation. |
| FB12250 | AEG 3482 | 63735-71-7 | AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. |