Notch
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB07177 | tCFA15 | 220757-88-0 | tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notchsignaling. |
| FB17711 | SAHM1 | 2050906-89-1 | SAHM1 is a stabilized hydrocarbon-stapled alpha helical peptide targeting Notch pathway. It mimics a dominant negative form of MAML, inhibits canonical Notch transcription complex formation. |
| FB18032 | RIN1 | N/A | RIN1 is a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ. It also blocked the functional interaction of RBPJ with SHARP, a scaffold protein that forms a transcriptional repressor complex with RBPJ in the absence of NOTCH signaling. |
| FB07066 | LY3039478 | 1421438-81-4 | LY3039478 is a novel, potent Notch inhibitor with an IC50 of 0.41 nM. |
| FB09925 | IMR-1A | 331862-41-0 | IMR-1A is the metabolite of IMR-1, a Notch inhibitor targeting the transcriptional activation. |
| FB09924 | IMR-1 | 310456-65-6 | IMR-1 is a cell penetrant and potent inhibitor of Notch transcriptional activation complex with IC50 of 6 μM for targeting the transcriptional activation. |
| FB04887 | FLI-06 | 313967-18-9 | FLI-06 is a Notch signaling inhibitor with EC50 of 2.3 μM which can disrupt Notch trafficking and processing. |
| FB03307 | BMS-983970 | 1584713-87-0 | BMS-983970 is an oral pan-Notch inhibitor for the treatment of cancer. |