The LanC-like protein superfamily encompasses a highly divergent group of peptide-modifying enzymes, including the eukaryotic and bacterial lanthionine synthetase C-like proteins (LanC); subtilin biosynthesis protein SpaC from Bacillus subtilis; epidermin biosynthesis protein EpiC from Staphylococcus epidermidis; nisin biosynthesis protein NisC from Lactococcus lactis; GCR2 from Arabidopsis thaliana (Mouse-ear cress); and many others.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17560 | BT-11 | 1912399-75-7 | BT-11 is a LANCL2-binding compound for treating inflammatory bowel disease. Oral treatment with BT-11 at 8 mg/kg/d in a mouse model of inflammatory bowel disease resulted in lowering the disease activity index, decreasing colonic inflammatory lesions, and suppressing inflammatory markers (e.g., TNF-α, and interferon-γ) in the gut. |