RSK
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB09875 | SL0101 | 77307-50-7 | SL0101 is a selective inhibitor of ribosomal S6 kinase (RSK) (IC50 = 89 nM for RSK2) which does not inhibit upstream kinases such as MEK, Raf and PKC. SL0101 Inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line. |
| FB08623 | PF-4708671 | 1255517-76-0 | PF-4708671 is an inhibitor of S6K1 (p70 ribosomal S6 kinase 1) with Ki and IC50 of 20 nM and 160 nM, respectively. |
| FB09915 | M2698 | 1379545-95-5 | MSC2363318A, also known as M2698, is an orally available inhibitor of the serine/threonine protein kinases ribosomal protein S6 Kinase (p70S6K) and Akt (protein kinase B), with potential antineoplastic activity. |
| FB01989 | LY2584702 Tosylate | 1082949-68-5 | LY2584702 tosylate salt is an inhibitor of p70S6K signaling and can prevent the phosphorylation of S6 subunit of ribosomes. |
| FB08078 | LY2584702 | 1082949-67-4 | LY2584702 is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes. |
| FB01988 | LY2584702 HCl | 1082948-81-9 | LY2584702 HCl is an orally available inhibitor of p70S6K signaling and inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes. |
| FB03944 | LJI308 | 1627709-94-7 | LJI308 is a potent pan-RSK inhibitor, with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. |
| FB03945 | LJH685 | 1627710-50-2 | LJH685 is a potent pan-RSK inhibitor with IC50 of 6 nM, 5 nM and 4 nM for RSK1, RSK2, and RSK3, respectively. |
| FB07513 | FMK | 821794-92-7 | FMK is an an irreversible RSK2 kinase inhibitor, that covalently modifies the C-terminal kinase domain of RSK. |
| FB06300 | CMK | 821794-90-5 | CMK is a RSK2 kinase inhibitor, used for cancer treatment. |
| FB02729 | BIX-02565 | 1311367-27-7 | BIX-02565 is a ribosomal S6 kinase 2 (RSK2) inhibitor with an IC50 of 1.1 nM. |
| FB02037 | BI-D1870 | 501437-28-1 | BI-D1870 is an inhibitor of S6 ribosome which can inhibit RSK1, RSK2, RSK3, RSK4 with IC50 of 31 nM, 24 nM, 18 nM and 15 nM, respectively. |