LPA Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB15211 | Lysophosphatidic Acid | 325465-93-8 | Lysophosphatidic Acid is a water-soluble endogenous phospholipid in serum acting as ligand activator for EDG-2 and EDG-4 (LPA) receptors. |
| FB06553 | LPA2 Antagonist 1 | 1017606-66-4 | LPA2 antagonist 1 is an LPA2 antagonist with an IC50 of 17 nM. |
| FB02488 | Ki16425 | 355025-24-0 | Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6. |
| FB07581 | Ki16198 | 355025-13-7 | Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6. |
| FB09051 | AM966 | 1228690-19-4 | AM966 is a high affinity, selective, oral LPA1 (lysophosphatidic acid receptor, IC50=17 nM) antagonist, with selectivity for this receptor over the other LPA receptors. |