Cannabinoid Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB03857 | WIN 55212-2 Mesylate | 131543-23-2 | WIN 55212-2 mesylate is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. |
| FB00724 | WIN 55212-2 | 131543-22-1 | WIN 55212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. |
| FB16890 | VDM 11 | 313998-81-1 | VDM 11 is a selective inhibitor of the anandamide membrane transporter (AMT) with IC50 values of 4 - 11 μM. |
| FB08147 | UR-144 | 1199943-44-6 | UR-144 is a drug that acts as a selective full agonist of the peripheral cannabinoid receptor CB2, but with much lower affinity for the psychoactive CB1 receptor. |
| FB16891 | UCM 707 | 390824-20-1 | UCM 707 is an inhibitor of endocannabinoid transport and the IC50 values are 0.8 and 30 μM for the anandamide transporter and FAAH respectively. |
| FB16846 | TM38837 | 1253641-65-4 | TM38837 is a novel, largely peripherally restricted CB1 antagonist with limited penetrance to the brain. Oral dose of TM38837 (100 mg/kg) induced a significant increase in freezing behavior. |
| FB10280 | Taranabant (1R,2R)stereoisomer | 701977-08-4 | Taranabant(1R,2R)stereoisomer is the R-Enantiomer of taranabant. Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist. |
| FB03811 | Taranabant | 701977-09-5 | Taranabant is a cannabinoid 1 receptor inverse agonist with IC50 of 0.3 nM. |
| FB09849 | Rimonabant | 168273-06-1 | Rimonabant is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM. |
| FB02544 | Rimonabant HCl | 158681-13-1 | Rimonabant HCl is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM. |
| FB06250 | Otenabant | 686344-29-6 | Otenabant is a selective, potent and competitive CB1 receptor antagonist with Ki of 0.7 nM. |
| FB02069 | Otenabant HCl | 686347-12-6 | Otenabant HCl is a recently discovered selective, high affinity, competitive CB1 receptor antagonist with Ki of 0.7 nM. |
| FB01782 | Org 27569 | 868273-06-7 | Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. |
| FB11773 | MK-9470 | 947371-30-4 | MK-9470 is a selective, high-affinity, inverse agonist (human IC50=0.7 nM) for the cannabinoid CB1 receptor (CB1R) developed for use in human brain imaging. |
| FB06761 | MDA 19 | 1048973-47-2 | MDA 19 is a selective human CB2 receptor agonist with Ki of 43.3 nM. |
| FB16545 | MAFP | 188404-10-6 | MAFP is a potent, irreversible inhibitor of fatty acid amide hydrolase (FAAH, anandamide amidase), the enzyme responsible for anandamide hydrolysis (IC50 = 2.5 nM). MAFP also binds irreversibly to CB1 receptors with IC50 of 20 nM. |
| FB06702 | LY320135 | 176977-56-3 | LY-320135 is a potent and selective Canniboid CB1 receptor antagonist/inverse agonist. LY-320135 is selective (~70 fold) over Canniboid CB2 receptors. This compound shows weak binding to both 5-HT2 (Ki = 6.4 μM) and muscarinic receptors (Ki = 2.1 μM). |
| FB00529 | JWH-133 | 259869-55-1 | JWH-133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over CB1 receptors. |
| FB01518 | JWH-073 | 208987-48-8 | JWH-018 is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. |
| FB11022 | JD5037 | 1392116-14-1 | JD-5037 is a peripherally restricted CB1R antagonist with an IC50 of 1.5 nM. |
| FB11846 | IP 751 | 137945-48-3 | IP 751 is a synthetic orally available analogue of a metabolite of Δ9-tetrahydrocannabinol, acts as a cannabinoid receptor agonist, with Kis of 5.7 nM, 56.1 nM and EC50s of 11.6 nM, 13.4 nM for hCB1 and hCB2 receptors, respectively, and has anti-inflammatory property. |
| FB10160 | GW842166X | 666260-75-9 | GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. |
| FB11624 | CB2R-IN-1 | 1257555-79-5 | CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM. |
| FB11242 | CB2 Agonist C8 | 2052602-31-8 | CB2 agonist C8 is an agonists of cannabinoid receptor type 2. |
| FB11243 | CB2 Agonist C36 | 2097512-96-2 | CB2 agonist C36 is an agonists of cannabinoid receptor type 2. |
| FB07199 | CB1-IN-1 | 1429239-98-4 | CB1-IN-1 is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. |
| FB08492 | BML-190 | 2854-32-2 | BML-190 is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor. |
| FB08216 | beta-Amyrin | 559-70-6 | beta-Amyrin, a natural cannabinoid receptors agonist isolated and purified from the stem bark of Alstonia boonei, has anti-inflammatory activity. Beta-Amyrin significantly inhibits PGE2, IL-6 secretion, and NF-κB activation in a concentration-dependent manner on LPS-induced hPBMCs. |
| FB06611 | beta-Amyrin Acetate | 1616-93-9 | beta-Amyrin acetrate, a natural cannabinoid receptor isolated and purified from the herbs of Alstonia boone, shows significant HMG-CoA-reductase and sEH inhibitory activities. |
| FB07274 | BAY 59-3074 | 406205-74-1 | Bay 59-3074 is a selective CB1/CB2 receptor partial agonist with Kis of 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively . |
| FB16880 | Arvanil | 128007-31-8 | Arvanil is an antagonist of cannabinoid CB1 and vanilloid TRPV1 (VR1) with Ki values are 0.5 and 0.3 μM respectively. |
| FB07433 | AM630 | 164178-33-0 | AM630 is a selectivity CB2 antagonist with Ki of 31.2 nM with a > 150 fold selectivity over CB1 receptor. |
| FB07636 | AM251 | 183232-66-8 | AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors and also a potent GPR55 agonist (EC50 = 39 nM). |
| FB02605 | AM1241 | 444912-48-5 | AM1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibiting 82-fold selectivity over CB1 receptor. |
| FB08673 | AKB 48 | 1345973-53-6 | AKB48 is a drug that acts as a reasonably potent agonist for the cannabinoid receptors, with a Ki of 304.5nM and an EC50 of 585nM at CB1. |
| FB07168 | A-836339 | 959746-77-1 | A-836339 is a cannabinoid CB2 receptor-selective agonist and exhibits high potencies at CB(2) and selectivity over CB(1) receptors. |
| FB02582 | AZ-037 | 2044702-46-5 | 5F-AB-FUPPYCA is a pyrazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. |
| FB05743 | (±)-SLV319 | 362519-49-1 | (±)-SLV319 is a selective antagonist of cannabinoid-1 (CB1) receptor with Ki value of 7.8 nM and it has a weaker activation effect on CB2. |
| FB05349 | (-)-Gallocatechin | 3371-27-5 | (-)-Gallocatechin, a natural product isolated and purified from the wood of Acacia catechu (L.F.) Willd., has moderate affinity to the human cannabinoid receptor. |
| FB06610 | (+)-Gallocatechin | 970-73-0 | (+)-Gallocatechin, a natural product isolated and purified from the wood of Acacia catechu (L.F.) Willd., has moderate affinity to the human cannabinoid receptor. |
| FB12152 | CP 55,940 | 83002-04-4 |