TAK1
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
FB11589 | Takinib | 1111556-37-6 | Takinib is a selective TAK1 inhibitor with IC50 of 9.5 nM, it can induce apoptosis in a TNF-α-dependent manner in rheumatoid arthritis (RA) and breast cancer models. |
FB02448 | NG25 | 1315355-93-1 | NG25, a TAK1 inhibitor, inhibiting the activation of IKK by TLR7 and TLR9 agonists and preventing the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells. |