| FB00290 |
Torsemide
|
56211-40-6 |
Torsemide is a medication mainly used in the management of fluid overload and peripheral edema associated with congestive heart failure. |
| FB09390 |
Sodium Gluconate
|
527-07-1 |
Sodium Gluconate is the sodium salt of gluconic acid with chelating property. |
| FB16631 |
o-Phenanthroline
|
66-71-7 |
o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm. |
| FB16621 |
Deferiprone
|
30652-11-0 |
Deferiprone is the only orally active iron-chelating drug to be used therapeutically in conditions of transfusional iron overload.
Target：
Deferiprone is an orphan drug designed and developed primarily by academic initiatives for the treatment of iron overload in thalassaemia. Deferiprone has been used in several other iron or other metal imbalance conditions and has prospects of wider clinical applications. Deferiprone has high affinity for iron and interacts with almost all the iron pools at the molecular, cellular, tissue and organ levels. Doses of 50-120 mg/kg/day appear to be effective in bringing patients to negative iron balance. Deferiprone increases urinary iron excretion, which mainly depends on the iron load of patients and the dose of the drug. |