DPP4
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB10867 | ZY15557 | 1601480-12-9 | ZY15557 is a potent, competitive and long acting DPP-4 inhibitor showing similar DPP-4 inhibition across different species. |
| FB10509 | Vildagliptin | 274901-16-5 | Vildagliptin is an inhibitor of DPP-4 with IC50 of 2.3 nM that is used in the treatment of type 2 diabetes mellitus. |
| FB11655 | Vildagliptin Dihydrate | 2133364-01-7 | Vildagliptin (LAF237 dihydrate;NVP-LAF 237 dihydrate) is a dipeptidyl peptidase 4 (DPP4) inhibitor that delays the degradation of glucagon-like peptide-1 (GLP-1). |
| FB00600 | Trelagliptin Succinate | 1029877-94-8 | Trelagliptin succinate is an highly selective inhibitor of dipeptidyl peptidase-4 (DPP-4) that is used for the treatment of type 2 diabetes. |
| FB00607 | Trelagliptin | 865759-25-7 | Trelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). |
| FB00473 | Teneligliptin | 760937-92-6 | Teneligliptin is a potent and long-lasting dipeptidyl peptidase-4 inhibitor, and competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM. |
| FB07549 | Teneligliptin Hydrobromide | 906093-29-6 | Teneligliptin Hydrobromide is a DPP4 inhibitor with IC50 value of <1 nM. It is commonly used as an add on treatment when meformin is not achieving the expected glycemic goals. |
| FB08461 | Talabostat Mesylate | 150080-09-4 | Talabostat mesilate is an orally active, specific inhibitor of dipeptidyl peptidases with IC50 of 1 nM for DPP4, including tumor-associated fibroblast activation protein. |
| FB10451 | Sitagliptin Phosphate Monohydrate | 654671-77-9 | Sitagliptin Phosphate Monohydrate is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts. |
| FB10663 | Sitagliptin Phosphate | 654671-78-0 | Sitagliptin phosphate is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts. |
| FB06342 | Sitagliptin | 486460-32-6 | Sitagliptin is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts. |
| FB00182 | Saxagliptin Hydrate | 945667-22-1 | Saxagliptin, the monohydrate form of anhydrous saxagliptin, is a reversible and selective DPP4 inhibitor with IC50 of 26 nM. It is used for the treatment of type 2 diabetes. |
| FB15902 | Saxagliptin HCl | 709031-78-7 | Saxagliptin, also known as BMS-477118, is a new oral hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin was approved in 2008 for the treatment of type 2 diabetes. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones, thereby increasing their bloodstream concentrations and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus. . |
| FB02424 | Saxagliptin | 361442-04-8 | Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM. |
| FB11756 | Saikogenin A | 5092-09-1 | Saikogenin A, extracted from a Chinese herbal plant called Tsai-Fu, is a dipeptidyl peptidase-IV (DPP-IV) inhibitor. |
| FB11268 | Retagliptin Phosphate | 1256756-88-3 | Retagliptin phosphate is a DPP-4 inhibitor potentially used for the treatment of Type 2 diabetes. |
| FB11266 | Retagliptin | 1174122-54-3 | Retagliptin is a DPP-4 inhibitor potentially used for the treatment of Type 2 diabetes. |
| FB11267 | Retagliptin HCl | 1174038-86-8 | Retagliptin HCl is a DPP-4 inhibitor potentially used for the treatment of Type 2 diabetes. |
| FB16918 | PK 44 phosphate | 1017682-66-4 | PK 44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) with IC50 of 15.8 nM. |
| FB00950 | Omarigliptin | 1226781-44-7 | Omarigliptin, also called MA-3102, is an selective inhibitor of DPP-4 with IC50 of 1.6 nM and Ki of 0.8 nM. Its selectivity is higher than other 168 proteasomes. |
| FB17154 | NVP DPP 728 dihydrochloride | 207556-62-5 | NVP DPP 728 dihydrochloride is active dipeptidyl peptidase (DPP)-IV inhibitor with Ki and IC50 of 11 nM, 14 nM respectively. |
| FB02117 | Linagliptin | 668270-12-0 | Linagliptin, a purine and quinazoline derivative, can inhibit DPP-4 with IC50 of 1 nM. It functions as an incretin and is used as a hypoglycemic agents in the treatment of type 2 diabetes mellitus. |
| FB16916 | K 579 | 440100-64-1 | K 579 is an inhibitor of dipeptidyl peptidase IV with IC50 value of 8 nM. |
| FB11123 | HBK001 | 1942922-78-2 | HBK001 is a dual DPP4 inhibitor and GPR119 agonist that regulates glycemic control and beta cell function ex and in vivo. |
| FB06769 | Gemigliptin | 911637-19-9 | Gemigliptin is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. |
| FB11334 | Evogliptin Tartrate | 1222102-51-3 | Evogliptin tartrate is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) which improves insulin resistance and delays the onset of diabetes. |
| FB11332 | Evogliptin | 1222102-29-5 | Evogliptin is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) which improves insulin resistance and delays the onset of diabetes. |
| FB11333 | Evogliptin HCl | 1246960-27-9 | Evogliptin HCl is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) which improves insulin resistance and delays the onset of diabetes. |
| FB16913 | DPPI 1c HCl | 866396-70-5 | DPPI 1c hydrochloride is inhibitor of dipeptidyl peptidase IV (DPP-IV) with IC50 of 104 nM. |
| FB16919 | Diprotin A | 90614-48-5 | Diprotin A is the inhibitor of dipeptidyl peptidase IV. It can inhibit entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines. |
| FB02325 | DBPR108 | 1186426-66-3 | DBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM showing no inhibition on DDP8 and DPP9. |
| FB16683 | Saxagliptin impurity F | 361442-00-4 | Boc-3-hydroxy-1-adamantyl-D-glycine is used in the preparation of a Saxagliptin intermediate. |
| FB05548 | Anagliptin | 739366-20-2 | Anagliptin is a potent and selective DPP-4 inhibitor(IC50= 3.8 nM) and > 10 fold less potent for DPP-8 and DPP-9. |
| FB07530 | Alogliptin | 850649-61-5 | Alogliptin is a dipeptidyl peptidase 4 (DPP-4) inhibitor with IC50 of 6.9 nM that exhibits greater selective than DPP-2, DPP-8 and DPP-9. |
| FB02112 | Alogliptin Benzoate | 850649-62-6 | Alogliptin benzoate is the benzoate salt form of alogliptin which is a selective inhibitor of DPP-4 with IC50 of 6.9 nM that exhibits greater selective than DPP-2, DPP-8 and DPP-9. |
| FB16670 | (2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetic acid | 709031-29-8 | 3-Hydroxy-1-adamantyl-D-glycine is a non-proteinogenic amino acid , which is a key intermediate required for the synthesis of Saxagliptin (S143500). |