Carbonic Anhydrase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB01600 | U-104 | 178606-66-1 | U-104 is a potent carbonic anhydrase (CA) inhibitor with Ki of 45.1 nM and 4.5 nM for CA IX and CA XII, respectively. |
| FB06678 | Tioxolone | 4991-65-5 | Tioxolone, a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM, is an anti-acne preparation. |
| FB09634 | Sultiame | 61-56-3 | Sultiame is an inhibitor of carbonic anhydrase that used to treat epilepsy. |
| FB16911 | S4 | 1330061-67-0 | S4 is a selective inhibitor of CA IX and CA XII inhibitor. The Ki values are 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively. |
| FB04177 | Methocarbamol | 532-03-6 | Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. |
| FB04175 | Methazolamide | 554-57-4 | Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. |
| FB01853 | Mafenide HCl | 138-37-4 | Mafenide HCl is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as a topical anti-bacterial agent, especially in burn therapy. |
| FB02880 | Indisulam | 165668-41-7 | Indisulam is a carbonic anhydrase inhbitor and a synthetic sulfonamide targeting the G1 phase of the cell cycle. |
| FB18288 | EMAC10101d | 2561476-24-0 | EMAC10101d is a potent and selective Carbonic Anhydrase II inhibitor. |
| FB01182 | Dorzolomide HCl | 130693-82-2 | Dorzolomide HCl is a potent and water-soluble inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM respectively and used as anti-glaucoma agent. |
| FB03543 | Dorzolamide | 120279-96-1 | Dorzolamide is an anti-glaucoma agent, which is a carbonic anhydrase inhibitor. |
| FB00434 | Diclazuril | 101831-37-2 | Diclazuril is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma. |
| FB00432 | Dichlorphenamide | 120-97-8 | Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor with Kis of 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively. |
| FB08292 | Brinzolamide | 138890-62-7 | Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. |
| FB15323 | BENZTHIAZIDE | 91-33-8 | Benzthiazide is a long-acting diuretic[1] and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells[2]. |
| FB03886 | Benzenesulfonamide | 98-10-2 | Benzenesulfonamide ia an inhibitor of carbonic anhydrases. |
| FB09052 | Acetazolamide | 59-66-5 | Acetazolamide, a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP). |
| FB06670 | 2-Aminobenzenesulfonamide | 3306-62-5 | 2-Aminobenzenesulfonamide is a potent inhibitor of carbonic anhydrase B. |
| FB16328 | 1,3-Dimethyluracil | 874-14-6 | 1,3-Dimethyluracil is a methyl derivative of uric acid, found occasionally in human urine. |