RIP Kinase
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB02791 | WEHI-345 | 1354825-58-3 | WEHI-345 is a potent and selective inhibitor of RIPK2, with IC50 of 0.13 μM. |
| FB17195 | RIPA-56 | 1956370-21-0 | RIPA-56 is a RIP1 inhibitor with EC50 value of 28nM. It efficiently reduced TNFα-induced mortality and multi-organ damage. |
| FB10376 | RIP2 Kinase Inhibitor 2 | 1581270-11-2 | RIP2 kinase inhibitor 2 is a receptor interacting protein-2 (RIP2) kinase inhibitor. |
| FB10377 | RIP2 Kinase Inhibitor 1 | 1423186-80-4 | RIP2 kinase inhibitor 1 is a receptor interacting protein-2 (RIP2) kinase inhibitor. |
| FB19642 | PROTAC RIPK degrader-2 | 1801547-16-9 | PROTAC RIPK degrader-2 is a nonpeptidic PROTAC which potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation. |
| FB07959 | Necrostatin 1 | 4311-88-0 | Necrostatin-1 is an inhibitor of RIP1 and can decrease TNF-α-induced necroptosis with EC50 of 490 nM. |
| FB13158 | HS1371 | 2158197-70-5 | HS1371 is an ATP-competitive and novel kinase inhibitor of RIP3-mediated necroptosis which can directly bind to RIP3. |
| FB02772 | GSK583 | 1346547-00-9 | GSK583 is a selective inhibitor of RIP2 Kinase and IC50 value is 5 nM. |
| FB16774 | GSK3145095 | 1622849-43-7 | GSK3145095 is a potent and orally active RIPK1 inhibitor with IC50 of 5 nM and potential antineoplastic and immunomodulatory activities. |
| FB16473 | GSK2983559 | 1579965-12-0 | GSK2983559 free acid is a small-molecule inhibitor of RIP2 kinase. GSK2983559 free acid potently binds to RIP2 kinase with good kinase specificity and has excellent activity in blocking many proinflammatory cytokine responses in vivo . |
| FB00771 | GSK2982772 | 1622848-92-3 | GSK2982772 is an inhibitor of receptor interacting protein 1 (RIP1) with IC50 of 16 nM and it is used for the treatment of inflammatory diseases. |
| FB15407 | GSK'547 | 2226735-55-1 | GSK'547 is a highly selective and potent RIP1 inhibitor with improved oral bioavailability. |